Correlation between animal and mathematical models for prostate cancer progression

Zdzislaw Jackiewicz, C. L. Jorcyk, M. Kolev, B. Zubik-Kowal

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

This work demonstrates that prostate tumour progression in vivo can be analysed by using solutions of a mathematical model supplemented by initial conditions chosen according to growth rates of cell lines in vitro. The mathematical model is investigated and solved numerically. Its numerical solutions are compared with experimental data from animal models. The numerical results confirm the experimental results with the growth rates in vivo.

Original languageEnglish (US)
Pages (from-to)241-252
Number of pages12
JournalComputational and Mathematical Methods in Medicine
Volume10
Issue number4
DOIs
StatePublished - Dec 1 2009

Keywords

  • Animal models for prostate cancer
  • Growth rates in vivo
  • Growth rates of Pr-cell lines in vitro
  • Mathematical model
  • Numerical simulations
  • Prostate tumour progression

ASJC Scopus subject areas

  • Modeling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Applied Mathematics

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