TY - JOUR
T1 - Copper/Silver Bimetallic Nanoparticles Supported on Aluminosilicate Geomaterials as Antibacterial Agents
AU - Cruces, Edgardo
AU - Arancibia-Miranda, Nicolás
AU - Manquián-Cerda, Karen
AU - Perreault, François
AU - Bolan, Nanthi
AU - Azócar, Manuel Ignacio
AU - Cubillos, Victor
AU - Montory, Jaime
AU - Rubio, María Angélica
AU - Sarkar, Binoy
N1 - Funding Information:
The authors thank Plan de Fortalecimiento de Universidades Estatales (ATA20992). This study was also supported by the FONDECYT Grant No. 11171079 and Basal Funding for Scientific and Technological Centers under Project AFB 180001 CEDENNA to E.C., and Agencia Nacional de Investigación (ANID) funding under PAI Program (PAI 771900) to K.M.-C. B.S. was supported by the Lancaster Environment Centre Project.
Funding Information:
The authors thank Plan de Fortalecimiento de Universidades Estatales (ATA20992). This study was also supported by the FONDECYT Grant No. 11171079 and Basal Funding for Scientific and Technological Centers under Project AFB 180001 CEDENNA to E.C., and Agencia Nacional de Investigacio?n (ANID) funding under PAI Program (PAI 771900) to K.M.-C. B.S. was supported by the Lancaster Environment Centre Project.
Publisher Copyright:
© 2022 American Chemical Society
PY - 2022/1/28
Y1 - 2022/1/28
N2 - This study aims to understand how properties of modified aluminosilicate geomaterials influence the antibacterial performance of nanocomposites when prepared with bimetallic nanoparticles (NPs). Copper/silver (Cu/Ag) bimetallic NPs were synthesized in the presence of imogolite (Imo), montmorillonite (Mtt), or zeolite (Zeo) using a simple one-pot method and characterized for their crystal phases, micro- and nanomorphologies, particle size, elemental composition, and electrophoretic mobility. The antibacterial activity was evaluated through minimum inhibition concentration assays of NPs and nanocomposites for Gram (−) Escherichia coli and Gram (+) Staphylococcus aureus bacteria. Deposition of metallic Cu0, Ag0, and cuprite NPs was confirmed in Zeo_Cu/Ag and Imo_Cu/Ag nanocomposites, whereas only Cu0 and Ag0 were identified in Mtt_Cu/Ag. The bimetallic NPs were more uniformly distributed on Zeo and Mtt than Imo. Particle sizes of 28.1 ± 5.0, 9.4 ± 2.3, 10.1 ± 1.7, and 12 ± 1.3 nm were determined for Cu/Ag NPs, Imo_Cu/Ag, Mtt_Cu/Ag, and Zeo_Cu/Ag, respectively. The release rate of Cu and Ag ions from Zeo_Cu/Ag was higher than those of pristine Cu/Ag NPs and the other two nanocomposites. The antimicrobial action of bimetallic NPs and nanocomposites was dose-dependent in relation to the concentration of concerned materials and their stability in the medium. The physicochemical characteristics of Zeo resulted in a homogeneous distribution and low oxidation and agglomeration of Cu/Ag NPs, consequently increasing the antibacterial activity. Results of this study highlight the benefits of using a geomaterial support to achieve high antibacterial activity of bimetallic NPs, which could help reduce the consumption of pure Cu/Ag salts in NP-based antibacterial applications.
AB - This study aims to understand how properties of modified aluminosilicate geomaterials influence the antibacterial performance of nanocomposites when prepared with bimetallic nanoparticles (NPs). Copper/silver (Cu/Ag) bimetallic NPs were synthesized in the presence of imogolite (Imo), montmorillonite (Mtt), or zeolite (Zeo) using a simple one-pot method and characterized for their crystal phases, micro- and nanomorphologies, particle size, elemental composition, and electrophoretic mobility. The antibacterial activity was evaluated through minimum inhibition concentration assays of NPs and nanocomposites for Gram (−) Escherichia coli and Gram (+) Staphylococcus aureus bacteria. Deposition of metallic Cu0, Ag0, and cuprite NPs was confirmed in Zeo_Cu/Ag and Imo_Cu/Ag nanocomposites, whereas only Cu0 and Ag0 were identified in Mtt_Cu/Ag. The bimetallic NPs were more uniformly distributed on Zeo and Mtt than Imo. Particle sizes of 28.1 ± 5.0, 9.4 ± 2.3, 10.1 ± 1.7, and 12 ± 1.3 nm were determined for Cu/Ag NPs, Imo_Cu/Ag, Mtt_Cu/Ag, and Zeo_Cu/Ag, respectively. The release rate of Cu and Ag ions from Zeo_Cu/Ag was higher than those of pristine Cu/Ag NPs and the other two nanocomposites. The antimicrobial action of bimetallic NPs and nanocomposites was dose-dependent in relation to the concentration of concerned materials and their stability in the medium. The physicochemical characteristics of Zeo resulted in a homogeneous distribution and low oxidation and agglomeration of Cu/Ag NPs, consequently increasing the antibacterial activity. Results of this study highlight the benefits of using a geomaterial support to achieve high antibacterial activity of bimetallic NPs, which could help reduce the consumption of pure Cu/Ag salts in NP-based antibacterial applications.
KW - Cu/Ag bimetallic nanoparticles
KW - antibacterial activity
KW - imogolite
KW - montmorillonite
KW - supported nanoparticles
KW - zeolite
UR - http://www.scopus.com/inward/record.url?scp=85122758996&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85122758996&partnerID=8YFLogxK
U2 - 10.1021/acsanm.1c04031
DO - 10.1021/acsanm.1c04031
M3 - Article
AN - SCOPUS:85122758996
SN - 2574-0970
VL - 5
SP - 1472
EP - 1483
JO - ACS Applied Nano Materials
JF - ACS Applied Nano Materials
IS - 1
ER -