Convolutamydine A, a novel bioactive hydroxyoxindole alkaloid from marine bryozoan Amathia convoluta

Yoshiaki Kamano, Hui ping Zhang, Yoshitatsu Ichihara, Haruhisa Kizu, Kanki Komiyama, George Pettit

Research output: Contribution to journalArticlepeer-review

238 Scopus citations

Abstract

Convolutamydine A (1), a new alkaloid containing a dibromohydroxyoxindole moiety, was isolated from the Floridian bryozoan Amathia convoluta and the structure was elucidated on the basis of spectroscopic data. Compound 1 exhibited a potent activity in the differentiation of HL-60 cells.

Original languageEnglish (US)
Pages (from-to)2783-2784
Number of pages2
JournalTetrahedron Letters
Volume36
Issue number16
DOIs
StatePublished - Apr 17 1995

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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