Contactless fluorescence imaging with a CMOS image sensor

Andreas G. Andreou, Zhaonian Zhang, Recep Özgün, Edward T. Choi, Zaven K. Kalayjian, Miriam A. Marwick, Jennifer Blain Christen, Leslie Tung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

In this work, we utilize a CMOS active pixel sensor in a fluorescence imaging setup. The ability to sense small light intensity changes on top of a large baseline with spatial resolution at the subcellular scale is required in fluorescence imaging. The CMOS imager presented in [1] is perfect for this application with the ability to resolve fine features coupled with high dynamic range. By using a custom imager with a relay lens we are able to realize a dramatic decrease in device size, cost and complexity of the whole system.

Original languageEnglish (US)
Title of host publication2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011
Pages2341-2344
Number of pages4
DOIs
StatePublished - Aug 2 2011
Externally publishedYes
Event2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011 - Rio de Janeiro, Brazil
Duration: May 15 2011May 18 2011

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)0271-4310

Other

Other2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011
CountryBrazil
CityRio de Janeiro
Period5/15/115/18/11

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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  • Cite this

    Andreou, A. G., Zhang, Z., Özgün, R., Choi, E. T., Kalayjian, Z. K., Marwick, M. A., Blain Christen, J., & Tung, L. (2011). Contactless fluorescence imaging with a CMOS image sensor. In 2011 IEEE International Symposium of Circuits and Systems, ISCAS 2011 (pp. 2341-2344). [5938072] (Proceedings - IEEE International Symposium on Circuits and Systems). https://doi.org/10.1109/ISCAS.2011.5938072