### Abstract

Interaction of the immune system and the pathogens (population of bacteria, viruses, etc.) is considered as a dynamical system. Also, the spread of the disease in the population starts at the individual level. To understand the effect of the endemic environment on the variability of the immune system response, mostly the vulnerability, a model using an integro-differential is introduced from epidemiology to immunology in an effort to assess the impact of the pathogen's spread within the population on the immune system response of the individual. The model gives reasonable results and these suggest that the proportion of infected individuals in the population have an impact on the immune system behavior of an individual.

Original language | English (US) |
---|---|

Pages (from-to) | 63-70 |

Number of pages | 8 |

Journal | Mathematical Scientist |

Volume | 43 |

Issue number | 2 |

State | Published - Dec 1 2018 |

### Fingerprint

### Keywords

- Immune response
- Immunology-based model
- Infection
- Phenomenological model
- State of the immune system

### ASJC Scopus subject areas

- Materials Science(all)

### Cite this

*Mathematical Scientist*,

*43*(2), 63-70.

**Connecting immunology and epidemiology.** / Soho, Edme; Wirkus, Stephen.

Research output: Contribution to journal › Article

*Mathematical Scientist*, vol. 43, no. 2, pp. 63-70.

}

TY - JOUR

T1 - Connecting immunology and epidemiology

AU - Soho, Edme

AU - Wirkus, Stephen

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Interaction of the immune system and the pathogens (population of bacteria, viruses, etc.) is considered as a dynamical system. Also, the spread of the disease in the population starts at the individual level. To understand the effect of the endemic environment on the variability of the immune system response, mostly the vulnerability, a model using an integro-differential is introduced from epidemiology to immunology in an effort to assess the impact of the pathogen's spread within the population on the immune system response of the individual. The model gives reasonable results and these suggest that the proportion of infected individuals in the population have an impact on the immune system behavior of an individual.

AB - Interaction of the immune system and the pathogens (population of bacteria, viruses, etc.) is considered as a dynamical system. Also, the spread of the disease in the population starts at the individual level. To understand the effect of the endemic environment on the variability of the immune system response, mostly the vulnerability, a model using an integro-differential is introduced from epidemiology to immunology in an effort to assess the impact of the pathogen's spread within the population on the immune system response of the individual. The model gives reasonable results and these suggest that the proportion of infected individuals in the population have an impact on the immune system behavior of an individual.

KW - Immune response

KW - Immunology-based model

KW - Infection

KW - Phenomenological model

KW - State of the immune system

UR - http://www.scopus.com/inward/record.url?scp=85059664165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85059664165&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:85059664165

VL - 43

SP - 63

EP - 70

JO - Mathematical Scientist

JF - Mathematical Scientist

SN - 0312-3685

IS - 2

ER -