Abstract

Interaction of the immune system and the pathogens (population of bacteria, viruses, etc.) is considered as a dynamical system. Also, the spread of the disease in the population starts at the individual level. To understand the effect of the endemic environment on the variability of the immune system response, mostly the vulnerability, a model using an integro-differential is introduced from epidemiology to immunology in an effort to assess the impact of the pathogen's spread within the population on the immune system response of the individual. The model gives reasonable results and these suggest that the proportion of infected individuals in the population have an impact on the immune system behavior of an individual.

Original languageEnglish (US)
Pages (from-to)63-70
Number of pages8
JournalMathematical Scientist
Volume43
Issue number2
StatePublished - Dec 1 2018

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Immunology
Epidemiology
Immune system
Pathogens
Viruses
Bacteria
Dynamical systems

Keywords

  • Immune response
  • Immunology-based model
  • Infection
  • Phenomenological model
  • State of the immune system

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Connecting immunology and epidemiology. / Soho, Edme; Wirkus, Stephen.

In: Mathematical Scientist, Vol. 43, No. 2, 01.12.2018, p. 63-70.

Research output: Contribution to journalArticle

Soho, Edme ; Wirkus, Stephen. / Connecting immunology and epidemiology. In: Mathematical Scientist. 2018 ; Vol. 43, No. 2. pp. 63-70.
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