Computer-aided detection of pulmonary embolism: Influence on radiologists' detection performance with respect to vessel segments

Marco Das, Georg Mühlenbruch, Anita Helm, Annemarie Bakai, Marcos Salganicoff, Sven Stanzel, Jianming Liang, Matthias Wolf, Rolf W. Günther, Joachim Ernst Wildberger

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

The purpose was to assess the sensitivity of a CAD software prototype for the detection of pulmonary embolism in MDCT chest examinations with regard to vessel level and to assess the influence on radiologists' detection performance. Forty-three patients with suspected PE were included in this retrospective study. MDCT chest examinations with a standard PE protocol were acquired at a 16-slice MDCT. All patient data were read by three radiologists (R1, R2, R3), and all thrombi were marked. A CAD prototype software was applied to all datasets, and each finding of the software was analyzed with regard to vessel level. The standard of reference was assessed in a consensus read. Sensitivity for the radiologists and CAD software was assessed. Thirty-three patients were positive for PE, with a total of 215 thrombi. The mean overall sensitivity for the CAD software alone was 83% (specificity, 80%). Radiologist sensitivity was 77%=R3, 82%=R2, and R1=87%. With the aid of the CAD software, sensitivities increased to 98% (R1), 93% (R2), and 92% (R3) (p<0.0001). CAD performance at the lobar level was 87%, at the segmental 90% and at the subsegmental 77%. With the use of CAD for PE, the detection performance of radiologists can be improved.

Original languageEnglish (US)
Pages (from-to)1350-1355
Number of pages6
JournalEuropean Radiology
Volume18
Issue number7
DOIs
StatePublished - Jul 1 2008
Externally publishedYes

Keywords

  • Computer tomography angiogram (CTA)
  • Computer-aided detection (CAD)
  • Multidetector-row computed tomography (MDCT)
  • Pulmonary embolism (PE)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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