@article{4b4ceff4a9a34bedafe0e532a0777914,
title = "Complex evolutionary history of felid anelloviruses",
abstract = "Anellovirus infections are highly prevalent in mammals, however, prior to this study only a handful of anellovirus genomes had been identified in members of the Felidae family. Here we characterise anelloviruses in pumas (Puma concolor), bobcats (Lynx rufus), Canada lynx (Lynx canadensis), caracals (Caracal caracal) and domestic cats (Felis catus). The complete anellovirus genomes (n = 220) recovered from 149 individuals were diverse. ORF1 protein sequence similarity network analysis coupled with phylogenetic analysis, revealed two distinct clusters that are populated by felid-derived anellovirus sequences, a pattern mirroring that observed for the porcine anelloviruses. Of the two-felid dominant anellovirus groups, one includes sequences from bobcats, pumas, domestic cats and an ocelot, and the other includes sequences from caracals, Canada lynx, domestic cats and pumas. Coinfections of diverse anelloviruses appear to be common among the felids. Evidence of recombination, both within and between felid-specific anellovirus groups, supports a long coevolution history between host and virus.",
keywords = "Anelloviridae, Bobcat, Canada lynx, Caracal, Domestic cat, Puma, Torque teno virus",
author = "Simona Kraberger and Serieys, {Laurel EK} and C{\'e}cile Richet and Fountain-Jones, {Nicholas M.} and Guy Baele and Bishop, {Jacqueline M.} and Mary Nehring and Ivan, {Jacob S.} and Newkirk, {Eric S.} and Squires, {John R.} and Lund, {Michael C.} and Riley, {Seth PD} and Wilmers, {Christopher C.} and {van Helden}, {Paul D.} and {Van Doorslaer}, Koenraad and Melanie Culver and Sue VandeWoude and Martin, {Darren P.} and Arvind Varsani",
note = "Funding Information: We thank Robert Fitak for his independent review and input for improving this manuscript. Sample collection of bobcat faecal material was supported by the National Park Service and Santa Monica Mountains Fund and Laurel Serieys was supported by an NSF graduate student fellowship. The caracal sampling was supported by Cape Leopard Trust and the Claude Leon Foundation . The puma and bobcat faecal material sampling from Mexico was supported by Primero Conservation ( www.primeroconservation.org ), Ron Thompson and Ivonne Cassaigne. G.B. acknowledges support from the Internal Fondsen KU Leuven /Internal Funds KU Leuven (Grant No. C14/18/094) and from the Research Foundation - Flanders (“Fonds voor Wetenschappelijk Onderzoek - Vlaanderen”, G0E1420 N, G098321 N). The molecular work was supported by philanthropic donations from Arvind Varsani and the Klein family. Funding Information: We thank Robert Fitak for his independent review and input for improving this manuscript. Sample collection of bobcat faecal material was supported by the National Park Service and Santa Monica Mountains Fund and Laurel Serieys was supported by an NSF graduate student fellowship. The caracal sampling was supported by Cape Leopard Trust and the Claude Leon Foundation. The puma and bobcat faecal material sampling from Mexico was supported by Primero Conservation (www.primeroconservation.org), Ron Thompson and Ivonne Cassaigne. G.B. acknowledges support from the Internal Fondsen KU Leuven/Internal Funds KU Leuven (Grant No. C14/18/094) and from the Research Foundation - Flanders (?Fonds voor Wetenschappelijk Onderzoek - Vlaanderen?, G0E1420 N, G098321 N). The molecular work was supported by philanthropic donations from Arvind Varsani and the Klein family. Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",
year = "2021",
month = oct,
doi = "10.1016/j.virol.2021.07.013",
language = "English (US)",
volume = "562",
pages = "176--189",
journal = "Virology",
issn = "0042-6822",
publisher = "Academic Press Inc.",
}