Combination drug treatment screening using a microfluidc cell array

Jeongyun Kim, David Taylor, Manjunath Hegde, Kaushal Rege, Arul Jayaraman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In this paper, we report the development of a microfluidic high-throughput screening system for the screening prostate cancer sensitizing agents. A key feature is that microfluidic system has 64 different combinatorial chambers with no diffusion and no flow, allowing the generation of the numerous concentrations required to optimize synergistic drug treatments.

Original languageEnglish (US)
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1494-1496
Number of pages3
ISBN (Print)9780979806421
StatePublished - Jan 1 2009
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: Nov 1 2009Nov 5 2009

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period11/1/0911/5/09

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Keywords

  • Doxorubicin
  • High-throughput screening
  • Sequential drug treatment
  • TRAIL

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Kim, J., Taylor, D., Hegde, M., Rege, K., & Jayaraman, A. (2009). Combination drug treatment screening using a microfluidc cell array. In Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1494-1496). (Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.