TY - JOUR
T1 - Cohort and age trends in age 35–45 prevalence of alcohol use disorder symptomology, by severity, sex, race, and education
AU - Jager, Justin
AU - Keyes, Katherine M.
AU - Son, Daye
AU - Kloska, Deb
AU - Patrick, Megan E.
AU - Schulenberg, John E.
N1 - Funding Information:
This research was supported by research grants from the National Institute on Alcohol Abuse and Alcoholism ( R01AA026861 to J. Jager and K. Keyes, R01AA023504 to M. E Patrick) and the National Institute of Drug Abuse ( R01DA037902 to M. E. Patrick, R01 DA001411 to R. Miech and L. Johnston, and R01DA016575 to J. E. Schulenberg and L. Johnston). The study sponsors had no role in the study design, collection, analysis, or interpretation of the data, writing of the manuscript, or the decision to submit the manuscript for publication. The content is solely the responsibility of the authors and does not necessarily represent the official views of the study sponsor.
Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Aims: To present national trends by age and cohort among middle-aged adults in the prevalence of AUD symptomology, by severity, sex, race, and education. Design: National, multi-cohort longitudinal probability samples of US adults, with data collected at ages 35, 40, and 45 among 14 cohorts who reached age 45 between 2003 and 2016. Setting: Data were collected via self-administered questionnaires to adults in the United States. Participants: The sample consisted of 20,634 individuals. Measurements: 5-year prevalence of symptoms consistent with a DSM-5 AUD. Findings: Between ages 35–45 prevalence of any AUD symptoms decreased 19 %; decreases were most evident between ages 35–40. From 2003 to 2016, AUD symptoms were steady across cohort. However, because the pace of decrease across ages 35–45 slowed across cohort, cohort differences emerged at specific ages: age 35 prevalence decreased 18 % across cohort, but age 45 prevalence was equivalent across cohort. Age and cohort effects, and their interaction, did not vary by AUD severity level. Declines in AUD symptoms across age were 17 % slower for women, and declines in AUD symptoms across age and cohort were 11 % and 29 % slower, respectively, for those with a college degree. The protection afforded by a college degree was reversed among mild AUD and most pronounced for severe AUD. Conclusions: AUDs may be more plastic and responsive to intervention during early mid-life than later. Despite progress in reducing the burden of AUD in the US population among younger middle-aged adults, an increased focus remains necessary as they continue to age.
AB - Aims: To present national trends by age and cohort among middle-aged adults in the prevalence of AUD symptomology, by severity, sex, race, and education. Design: National, multi-cohort longitudinal probability samples of US adults, with data collected at ages 35, 40, and 45 among 14 cohorts who reached age 45 between 2003 and 2016. Setting: Data were collected via self-administered questionnaires to adults in the United States. Participants: The sample consisted of 20,634 individuals. Measurements: 5-year prevalence of symptoms consistent with a DSM-5 AUD. Findings: Between ages 35–45 prevalence of any AUD symptoms decreased 19 %; decreases were most evident between ages 35–40. From 2003 to 2016, AUD symptoms were steady across cohort. However, because the pace of decrease across ages 35–45 slowed across cohort, cohort differences emerged at specific ages: age 35 prevalence decreased 18 % across cohort, but age 45 prevalence was equivalent across cohort. Age and cohort effects, and their interaction, did not vary by AUD severity level. Declines in AUD symptoms across age were 17 % slower for women, and declines in AUD symptoms across age and cohort were 11 % and 29 % slower, respectively, for those with a college degree. The protection afforded by a college degree was reversed among mild AUD and most pronounced for severe AUD. Conclusions: AUDs may be more plastic and responsive to intervention during early mid-life than later. Despite progress in reducing the burden of AUD in the US population among younger middle-aged adults, an increased focus remains necessary as they continue to age.
KW - Alcohol use disorder
KW - Cohort
KW - Middle-aged adults
KW - Sex
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U2 - 10.1016/j.drugalcdep.2021.108820
DO - 10.1016/j.drugalcdep.2021.108820
M3 - Article
C2 - 34245999
AN - SCOPUS:85110251633
VL - 226
JO - Drug and Alcohol Dependence
JF - Drug and Alcohol Dependence
SN - 0376-8716
M1 - 108820
ER -