TY - JOUR
T1 - Cognitive function as a mediator in the relationship between physical activity and depression status in older adults
AU - Birch, Kelly
AU - Hope, Merritt Ten
AU - Malek-Ahmadi, Michael
AU - O'Connor, Kathy
AU - Schofeld, Sharon
AU - Coon, David
AU - Nieri, Walter
N1 - Publisher Copyright:
© 2016 Human Kinetics, Inc.
PY - 2016/10
Y1 - 2016/10
N2 - Previous research has found that increased physical activity may provide a protective effect on depression status; however, these studies do not account for cognitive function. This study's aim was to determine whether cognitive function mediates the association between physical activity depression status in older adults. Data from 501 older adults were used for this analysis. Physical activity had a signifcant protective effect on depression (OR = 0.761, 95% CI [0.65, 0.89], p =.001). Adjusted analysis yielded an attenuated association (OR = 0.81, 95% CI [0.69, 0.95], p =.01) with a signifcant interaction for physical activity and cognitive function (OR = 0.991, 95% CI [0.985, 0.997], p =.005). MoCA performance also had a signifcant mediating effect on the relationship between physical activity and depression status (p =.04). These fndings suggest that cognitive function is associated with, and does mediate, the relationship between physical activity and depression status.
AB - Previous research has found that increased physical activity may provide a protective effect on depression status; however, these studies do not account for cognitive function. This study's aim was to determine whether cognitive function mediates the association between physical activity depression status in older adults. Data from 501 older adults were used for this analysis. Physical activity had a signifcant protective effect on depression (OR = 0.761, 95% CI [0.65, 0.89], p =.001). Adjusted analysis yielded an attenuated association (OR = 0.81, 95% CI [0.69, 0.95], p =.01) with a signifcant interaction for physical activity and cognitive function (OR = 0.991, 95% CI [0.985, 0.997], p =.005). MoCA performance also had a signifcant mediating effect on the relationship between physical activity and depression status (p =.04). These fndings suggest that cognitive function is associated with, and does mediate, the relationship between physical activity and depression status.
KW - Activity level
KW - Cognition
KW - Depression
KW - Geriatrics
KW - Physical activity
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U2 - 10.1123/japa.2015-0029
DO - 10.1123/japa.2015-0029
M3 - Article
C2 - 27051070
AN - SCOPUS:84995685166
SN - 1063-8652
VL - 24
SP - 540
EP - 546
JO - Journal of Aging and Physical Activity
JF - Journal of Aging and Physical Activity
IS - 4
ER -