Co-occurrence in nature of different clones of the social amoeba, Dictyostelium discoideum

Angelo Fortunato, J. E. Strassmann, L. Santorelli, D. C. Queller

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

The social amoeba, Dictyostelium discoideum, produces a multicellular fruiting body and has become a model system for cell-cell interactions such as signalling, adhesion and development. However, unlike most multicellular organisms, it forms by aggregation of cells and, in the laboratory, forms genetic chimeras where there may be competition among clones. Here we show that chimera formation is also likely in nature, because different clones commonly co-occur on a very small scale. This suggests that D. discoideum will likely have evolved strategies for competing in chimeras, and that the function of some developmental genes will be competitive. Natural chimerism also makes D. discoideum a good model organism for the investigation of issues relating to coexistence and conflict between cells.

Original languageEnglish (US)
Pages (from-to)1031-1038
Number of pages8
JournalMolecular Ecology
Volume12
Issue number4
DOIs
StatePublished - Apr 1 2003
Externally publishedYes

Fingerprint

chimera
Dictyostelium discoideum
Amoeba
Dictyostelium
chimerism
clone
Clone Cells
clones
Organism Forms
Developmental Genes
Cell Aggregation
Chimerism
fruiting
cells
adhesion
Cell Communication
coexistence
organisms
fruiting bodies
gene

Keywords

  • Chimera
  • Dictyostelium
  • Kin selection
  • Multicellularity
  • Relatedness
  • Slime mould

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics

Cite this

Co-occurrence in nature of different clones of the social amoeba, Dictyostelium discoideum. / Fortunato, Angelo; Strassmann, J. E.; Santorelli, L.; Queller, D. C.

In: Molecular Ecology, Vol. 12, No. 4, 01.04.2003, p. 1031-1038.

Research output: Contribution to journalArticle

Fortunato, Angelo ; Strassmann, J. E. ; Santorelli, L. ; Queller, D. C. / Co-occurrence in nature of different clones of the social amoeba, Dictyostelium discoideum. In: Molecular Ecology. 2003 ; Vol. 12, No. 4. pp. 1031-1038.
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