Clinical application of a new endoscopic technique for detection of in situ bronchial carcinoma

D. Cortese; J. H. Kinsey; L. B. Woolner; W. S. Payne; D. R. Sanderson; R. S. Fontana

Clinical application of a new endoscopic technique for detection of in situ bronchial carcinoma

D. Cortese, J. H. Kinsey, L. B. Woolner, W. S. Payne, D. R. Sanderson, R. S. Fontana

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Abstract

Hematoporphyrin is preferentially concentrated by cancer tissue and therefore is a potentially useful chemical marker. This report demonstrates the effectiveness of a photoelectric hematoporphyrin fluorescence detector used simultaneously with flexible fiberoptic bronchoscopy as a means of detecting and localizing bronchogenic carcinoma. The detector generates an audio signal when fluorescence is within the visual field of the bronchoscope. Of interest is that an audio signal was generated which indicated hematoporphyrin fluorescence in areas where no mucosal abnormality had been seen. These areas proved to be carcinoma in situ.

Original language	English (US)
Pages (from-to)	635-641
Number of pages	7
Journal	Mayo Clinic Proceedings
Volume	54
Issue number	10
State	Published - Dec 1 1979
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Clinical application of a new endoscopic technique for detection of in situ bronchial carcinoma",

abstract = "Hematoporphyrin is preferentially concentrated by cancer tissue and therefore is a potentially useful chemical marker. This report demonstrates the effectiveness of a photoelectric hematoporphyrin fluorescence detector used simultaneously with flexible fiberoptic bronchoscopy as a means of detecting and localizing bronchogenic carcinoma. The detector generates an audio signal when fluorescence is within the visual field of the bronchoscope. Of interest is that an audio signal was generated which indicated hematoporphyrin fluorescence in areas where no mucosal abnormality had been seen. These areas proved to be carcinoma in situ.",

author = "D. Cortese and Kinsey, {J. H.} and Woolner, {L. B.} and Payne, {W. S.} and Sanderson, {D. R.} and Fontana, {R. S.}",

year = "1979",

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language = "English (US)",

volume = "54",

pages = "635--641",

journal = "Mayo Clinic Proceedings",

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T1 - Clinical application of a new endoscopic technique for detection of in situ bronchial carcinoma

AU - Cortese, D.

AU - Kinsey, J. H.

AU - Woolner, L. B.

AU - Payne, W. S.

AU - Sanderson, D. R.

AU - Fontana, R. S.

PY - 1979/12/1

Y1 - 1979/12/1

N2 - Hematoporphyrin is preferentially concentrated by cancer tissue and therefore is a potentially useful chemical marker. This report demonstrates the effectiveness of a photoelectric hematoporphyrin fluorescence detector used simultaneously with flexible fiberoptic bronchoscopy as a means of detecting and localizing bronchogenic carcinoma. The detector generates an audio signal when fluorescence is within the visual field of the bronchoscope. Of interest is that an audio signal was generated which indicated hematoporphyrin fluorescence in areas where no mucosal abnormality had been seen. These areas proved to be carcinoma in situ.

AB - Hematoporphyrin is preferentially concentrated by cancer tissue and therefore is a potentially useful chemical marker. This report demonstrates the effectiveness of a photoelectric hematoporphyrin fluorescence detector used simultaneously with flexible fiberoptic bronchoscopy as a means of detecting and localizing bronchogenic carcinoma. The detector generates an audio signal when fluorescence is within the visual field of the bronchoscope. Of interest is that an audio signal was generated which indicated hematoporphyrin fluorescence in areas where no mucosal abnormality had been seen. These areas proved to be carcinoma in situ.

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M3 - Article

C2 - 480987

AN - SCOPUS:0018713705

SN - 0025-6196

VL - 54

SP - 635

EP - 641

JO - Mayo Clinic Proceedings

JF - Mayo Clinic Proceedings

IS - 10

ER -

Clinical application of a new endoscopic technique for detection of in situ bronchial carcinoma

Abstract

ASJC Scopus subject areas

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