Cliff-edged fitness functions and the persistence of schizophrenia

Randolph M. Nesse

doi:10.1017/S0140525X04300191

Cliff-edged fitness functions and the persistence of schizophrenia

Randolph M. Nesse

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Strong recent selection for social cognition may well explain the persistence of genes that predispose to schizophrenia. The specific mechanism responsible may be a skewed fitness function in which selection pushes the mean for advantageous mental traits perilously close to a "fitness cliff" where the system fails catastrophically in some individuals.

Original language	English (US)
Pages (from-to)	862-863
Number of pages	2
Journal	Behavioral and Brain Sciences
Volume	27
Issue number	6
DOIs	https://doi.org/10.1017/S0140525X04300191
State	Published - Dec 1 2004
Externally published	Yes

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Physiology
Behavioral Neuroscience

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Cliff-edged fitness functions and the persistence of schizophrenia

Abstract

ASJC Scopus subject areas

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