Cholangiocarcinoma in primary sclerosing cholangitis

Ghulam Abbas, Keith Lindor

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Introduction: Cholangiocarcinoma (CCA) is an aggressive and nearly always fatal tumor of the biliary tract. Purpose: This review explores risk factors, epidemiology, current diagnostic approaches, and treatment of CCA arising in patients with primary sclerosing cholangitis (PSC). Methods: We review latest recommendations about screening strategies to enable the early detection of CCA in PSC, using CA 19-9 and ultrasound imaging, as well as fluorescent in situ hybridization techniques to enhance the accuracy of biliary cytology. We also review the emerging role of liver transplantation.

Original languageEnglish (US)
Pages (from-to)19-25
Number of pages7
JournalJournal of Gastrointestinal Cancer
Volume40
Issue number1-2
DOIs
StatePublished - Jun 2009
Externally publishedYes

Fingerprint

Sclerosing Cholangitis
Cholangiocarcinoma
Biliary Tract
Fluorescence In Situ Hybridization
Liver Transplantation
Cell Biology
Ultrasonography
Epidemiology
Neoplasms
Therapeutics

Keywords

  • Cholangiocarcinoma
  • Diagnosis
  • Epidemiology
  • Primary sclerosing cholangitis
  • Treatment

ASJC Scopus subject areas

  • Gastroenterology
  • Oncology

Cite this

Cholangiocarcinoma in primary sclerosing cholangitis. / Abbas, Ghulam; Lindor, Keith.

In: Journal of Gastrointestinal Cancer, Vol. 40, No. 1-2, 06.2009, p. 19-25.

Research output: Contribution to journalArticle

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