Abstract
Introduction: Cholangiocarcinoma (CCA) is an aggressive and nearly always fatal tumor of the biliary tract. Purpose: This review explores risk factors, epidemiology, current diagnostic approaches, and treatment of CCA arising in patients with primary sclerosing cholangitis (PSC). Methods: We review latest recommendations about screening strategies to enable the early detection of CCA in PSC, using CA 19-9 and ultrasound imaging, as well as fluorescent in situ hybridization techniques to enhance the accuracy of biliary cytology. We also review the emerging role of liver transplantation.
Original language | English (US) |
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Pages (from-to) | 19-25 |
Number of pages | 7 |
Journal | Journal of Gastrointestinal Cancer |
Volume | 40 |
Issue number | 1-2 |
DOIs | |
State | Published - Jun 2009 |
Externally published | Yes |
Keywords
- Cholangiocarcinoma
- Diagnosis
- Epidemiology
- Primary sclerosing cholangitis
- Treatment
ASJC Scopus subject areas
- Oncology
- Gastroenterology