Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6

D. M. Magee; J. G. Smith; C. A. Bleicker; C. J. Carter; L. F. Bonewald; J. Schachter; D. M. Williams

Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6

D. M. Magee, J. G. Smith, C. A. Bleicker, C. J. Carter, L. F. Bonewald, J. Schachter, D. M. Williams

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1α, IL-1β, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.

Original language	English (US)
Pages (from-to)	1217-1220
Number of pages	4
Journal	Infection and immunity
Volume	60
Issue number	3
State	Published - 1992
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

Cite this

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title = "Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6",

abstract = "Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1α, IL-1β, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.",

author = "Magee, {D. M.} and Smith, {J. G.} and Bleicker, {C. A.} and Carter, {C. J.} and Bonewald, {L. F.} and J. Schachter and Williams, {D. M.}",

year = "1992",

language = "English (US)",

volume = "60",

pages = "1217--1220",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "3",

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TY - JOUR

T1 - Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6

AU - Magee, D. M.

AU - Smith, J. G.

AU - Bleicker, C. A.

AU - Carter, C. J.

AU - Bonewald, L. F.

AU - Schachter, J.

AU - Williams, D. M.

PY - 1992

Y1 - 1992

N2 - Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1α, IL-1β, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.

AB - Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1α, IL-1β, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.

UR - http://www.scopus.com/inward/record.url?scp=0026507246&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026507246&partnerID=8YFLogxK

M3 - Comment/debate

C2 - 1541536

AN - SCOPUS:0026507246

SN - 0019-9567

VL - 60

SP - 1217

EP - 1220

JO - Infection and Immunity

JF - Infection and Immunity

IS - 3

ER -

Chlamydia trachomatis pneumonia induces in vivo production of interleukin- 1 and -6

Abstract

ASJC Scopus subject areas

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