Cytokine induction during Chlamydia trachomatis pneumonia may alter the pathogenesis or course of disease. We examined interleukin-1 (IL-1) and IL-6 production by measuring mRNA and bioactivity in murine lungs. mRNA and bioactivity for IL-1α, IL-1β, and IL-6 increased after Chlamydia infection. These cytokines may be important in regulating host defenses against C. trachomatis.
|Original language||English (US)|
|Number of pages||4|
|Journal||Infection and immunity|
|State||Published - 1992|
ASJC Scopus subject areas
- Infectious Diseases