TY - JOUR
T1 - Childhood sexual abuse and impulsive personality traits
T2 - Mixed evidence for moderation by DRD4 genotype
AU - Harden, K. Paige
AU - Carlson, Marie D.
AU - Kretsch, Natalie
AU - Corbin, William
AU - Fromme, Kim
PY - 2015/4/1
Y1 - 2015/4/1
N2 - This project examines associations between childhood sexual abuse (CSA) and two dimensions of impulsivity (sensation seeking and premeditation), and tests whether CSA-personality associations are moderated by the DRD4 exon III VNTR polymorphism. Sample 1 is from a longitudinal study of university students measured at 10 waves over ages 18-24. years (n=500). Sample 2 is from a national sample of young adult sibling pairs, ages 18-24, from the National Longitudinal Study of Adolescent Health (n=2559). In both samples, CSA was associated with elevated sensation seeking. In Sample 1, the association between CSA and sensation seeking was moderated by DRD4 genotype; this gene. ×. environment interaction effect, however, was not replicated in Sample 2. Results suggest new avenues for research on CSA in the area of normal-range personality variation.
AB - This project examines associations between childhood sexual abuse (CSA) and two dimensions of impulsivity (sensation seeking and premeditation), and tests whether CSA-personality associations are moderated by the DRD4 exon III VNTR polymorphism. Sample 1 is from a longitudinal study of university students measured at 10 waves over ages 18-24. years (n=500). Sample 2 is from a national sample of young adult sibling pairs, ages 18-24, from the National Longitudinal Study of Adolescent Health (n=2559). In both samples, CSA was associated with elevated sensation seeking. In Sample 1, the association between CSA and sensation seeking was moderated by DRD4 genotype; this gene. ×. environment interaction effect, however, was not replicated in Sample 2. Results suggest new avenues for research on CSA in the area of normal-range personality variation.
KW - Childhood sexual abuse
KW - Diathesis stress
KW - Differential susceptibility
KW - DRD4
KW - Gene-environment interaction
KW - Impulsivity
KW - Sensation seeking
UR - http://www.scopus.com/inward/record.url?scp=84936933210&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84936933210&partnerID=8YFLogxK
U2 - 10.1016/j.jrp.2014.12.005
DO - 10.1016/j.jrp.2014.12.005
M3 - Article
AN - SCOPUS:84936933210
VL - 55
SP - 30
EP - 40
JO - Journal of Research in Personality
JF - Journal of Research in Personality
SN - 0092-6566
ER -