Childhood sexual abuse and impulsive personality traits: Mixed evidence for moderation by DRD4 genotype

K. Paige Harden, Marie D. Carlson, Natalie Kretsch, William Corbin, Kim Fromme

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This project examines associations between childhood sexual abuse (CSA) and two dimensions of impulsivity (sensation seeking and premeditation), and tests whether CSA-personality associations are moderated by the DRD4 exon III VNTR polymorphism. Sample 1 is from a longitudinal study of university students measured at 10 waves over ages 18-24. years (n=500). Sample 2 is from a national sample of young adult sibling pairs, ages 18-24, from the National Longitudinal Study of Adolescent Health (n=2559). In both samples, CSA was associated with elevated sensation seeking. In Sample 1, the association between CSA and sensation seeking was moderated by DRD4 genotype; this gene. ×. environment interaction effect, however, was not replicated in Sample 2. Results suggest new avenues for research on CSA in the area of normal-range personality variation.

Original languageEnglish (US)
Pages (from-to)30-40
Number of pages11
JournalJournal of Research in Personality
Volume55
DOIs
StatePublished - Apr 1 2015

Fingerprint

Sex Offenses
Personality
Genotype
National Longitudinal Study of Adolescent Health
Impulsive Behavior
Longitudinal Studies
Siblings
Young Adult
Exons
Reference Values
Students
Research
Genes

Keywords

  • Childhood sexual abuse
  • Diathesis stress
  • Differential susceptibility
  • DRD4
  • Gene-environment interaction
  • Impulsivity
  • Sensation seeking

ASJC Scopus subject areas

  • Social Psychology
  • Psychology(all)

Cite this

Childhood sexual abuse and impulsive personality traits : Mixed evidence for moderation by DRD4 genotype. / Harden, K. Paige; Carlson, Marie D.; Kretsch, Natalie; Corbin, William; Fromme, Kim.

In: Journal of Research in Personality, Vol. 55, 01.04.2015, p. 30-40.

Research output: Contribution to journalArticle

Harden, K. Paige ; Carlson, Marie D. ; Kretsch, Natalie ; Corbin, William ; Fromme, Kim. / Childhood sexual abuse and impulsive personality traits : Mixed evidence for moderation by DRD4 genotype. In: Journal of Research in Personality. 2015 ; Vol. 55. pp. 30-40.
@article{7366a8e5103248e1aa033776c24ed90a,
title = "Childhood sexual abuse and impulsive personality traits: Mixed evidence for moderation by DRD4 genotype",
abstract = "This project examines associations between childhood sexual abuse (CSA) and two dimensions of impulsivity (sensation seeking and premeditation), and tests whether CSA-personality associations are moderated by the DRD4 exon III VNTR polymorphism. Sample 1 is from a longitudinal study of university students measured at 10 waves over ages 18-24. years (n=500). Sample 2 is from a national sample of young adult sibling pairs, ages 18-24, from the National Longitudinal Study of Adolescent Health (n=2559). In both samples, CSA was associated with elevated sensation seeking. In Sample 1, the association between CSA and sensation seeking was moderated by DRD4 genotype; this gene. ×. environment interaction effect, however, was not replicated in Sample 2. Results suggest new avenues for research on CSA in the area of normal-range personality variation.",
keywords = "Childhood sexual abuse, Diathesis stress, Differential susceptibility, DRD4, Gene-environment interaction, Impulsivity, Sensation seeking",
author = "Harden, {K. Paige} and Carlson, {Marie D.} and Natalie Kretsch and William Corbin and Kim Fromme",
year = "2015",
month = "4",
day = "1",
doi = "10.1016/j.jrp.2014.12.005",
language = "English (US)",
volume = "55",
pages = "30--40",
journal = "Journal of Research in Personality",
issn = "0092-6566",
publisher = "Academic Press Inc.",

}

TY - JOUR

T1 - Childhood sexual abuse and impulsive personality traits

T2 - Mixed evidence for moderation by DRD4 genotype

AU - Harden, K. Paige

AU - Carlson, Marie D.

AU - Kretsch, Natalie

AU - Corbin, William

AU - Fromme, Kim

PY - 2015/4/1

Y1 - 2015/4/1

N2 - This project examines associations between childhood sexual abuse (CSA) and two dimensions of impulsivity (sensation seeking and premeditation), and tests whether CSA-personality associations are moderated by the DRD4 exon III VNTR polymorphism. Sample 1 is from a longitudinal study of university students measured at 10 waves over ages 18-24. years (n=500). Sample 2 is from a national sample of young adult sibling pairs, ages 18-24, from the National Longitudinal Study of Adolescent Health (n=2559). In both samples, CSA was associated with elevated sensation seeking. In Sample 1, the association between CSA and sensation seeking was moderated by DRD4 genotype; this gene. ×. environment interaction effect, however, was not replicated in Sample 2. Results suggest new avenues for research on CSA in the area of normal-range personality variation.

AB - This project examines associations between childhood sexual abuse (CSA) and two dimensions of impulsivity (sensation seeking and premeditation), and tests whether CSA-personality associations are moderated by the DRD4 exon III VNTR polymorphism. Sample 1 is from a longitudinal study of university students measured at 10 waves over ages 18-24. years (n=500). Sample 2 is from a national sample of young adult sibling pairs, ages 18-24, from the National Longitudinal Study of Adolescent Health (n=2559). In both samples, CSA was associated with elevated sensation seeking. In Sample 1, the association between CSA and sensation seeking was moderated by DRD4 genotype; this gene. ×. environment interaction effect, however, was not replicated in Sample 2. Results suggest new avenues for research on CSA in the area of normal-range personality variation.

KW - Childhood sexual abuse

KW - Diathesis stress

KW - Differential susceptibility

KW - DRD4

KW - Gene-environment interaction

KW - Impulsivity

KW - Sensation seeking

UR - http://www.scopus.com/inward/record.url?scp=84936933210&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84936933210&partnerID=8YFLogxK

U2 - 10.1016/j.jrp.2014.12.005

DO - 10.1016/j.jrp.2014.12.005

M3 - Article

AN - SCOPUS:84936933210

VL - 55

SP - 30

EP - 40

JO - Journal of Research in Personality

JF - Journal of Research in Personality

SN - 0092-6566

ER -