Chemical modifications of transfer RNA species. Heavy atom derivatization of aminoacyl tRNA

Francis J. Schmidt, Robert M. Bock, Sidney M. Hecht

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12 Scopus citations

Abstract

Specific heavy atom derivatization of valyl and arginyl tRNA's from E. coli has been effected by the use of the N-hydroxysuccinimide esters of certain carboxylic acids. The derivatized tRNA's have been separated from underivatized material and shown to be stable under the conditions required for crystallization.

Original languageEnglish (US)
Pages (from-to)451-456
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume48
Issue number2
DOIs
StatePublished - Jul 25 1972

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ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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