Characterizing the Transmission Dynamics and Control of Ebola Virus Disease

Gerardo Chowell, Hiroshi Nishiura

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Carefully calibrated transmission models have the potential to guide public health officials on the nature and scale of the interventions required to control epidemics. In the context of the ongoing Ebola virus disease (EVD) epidemic in Liberia, Drake and colleagues, in this issue of PLOS Biology, employed an elegant modeling approach to capture the distributions of the number of secondary cases that arise in the community and health care settings in the context of changing population behaviors and increasing hospital capacity. Their findings underscore the role of increasing the rate of safe burials and the fractions of infectious individuals who seek hospitalization together with hospital capacity to achieve epidemic control. However, further modeling efforts of EVD transmission and control in West Africa should utilize the spatial-temporal patterns of spread in the region by incorporating spatial heterogeneity in the transmission process. Detailed datasets are urgently needed to characterize temporal changes in population behaviors, contact networks at different spatial scales, population mobility patterns, adherence to infection control measures in hospital settings, and hospitalization and reporting rates.

Original languageEnglish (US)
JournalPLoS Biology
Volume13
Issue number1
DOIs
StatePublished - 2015

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Ebola Hemorrhagic Fever
Ebolavirus
Viruses
disease control
Hospitalization
Liberia
Population
Burial
Community Health Services
Western Africa
disease transmission
Infection Control
health services
control methods
public health
Public health
Public Health
Health care
Biological Sciences

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Neuroscience(all)

Cite this

Characterizing the Transmission Dynamics and Control of Ebola Virus Disease. / Chowell, Gerardo; Nishiura, Hiroshi.

In: PLoS Biology, Vol. 13, No. 1, 2015.

Research output: Contribution to journalArticle

Chowell, Gerardo ; Nishiura, Hiroshi. / Characterizing the Transmission Dynamics and Control of Ebola Virus Disease. In: PLoS Biology. 2015 ; Vol. 13, No. 1.
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