Characterization of viral double-stranded RNA-binding proteins

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Several viruses have been shown to code for proteins that specifically bind to double-stranded RNA or RNA with large amounts of secondary structure. These proteins have been implicated in providing interferon resistance to viruses and in inhibiting induction of apoptosis by viruses, and have been suggested to be involved in regulation of viral and cellular protein synthesis in infected cells. This article describes methods for detecting and analyzing viral double-stranded RNA-binding proteins.

Original languageEnglish (US)
Pages (from-to)225-232
Number of pages8
JournalMethods: A Companion to Methods in Enzymology
Volume15
Issue number3
DOIs
StatePublished - 1998

Fingerprint

RNA-Binding Proteins
Viral RNA
Viral Proteins
Viruses
Virus Activation
Double-Stranded RNA
Interferons
Proteins
RNA
Apoptosis

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Characterization of viral double-stranded RNA-binding proteins. / Jacobs, Bertram; Langland, Jeffrey; Brandt, T.

In: Methods: A Companion to Methods in Enzymology, Vol. 15, No. 3, 1998, p. 225-232.

Research output: Contribution to journalArticle

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