Characterization of three VNTR systems at D21S112

Norma Takaesu, Stuart Newfeld, Terry Hassold

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

D21S112 is a highly polymorphic marker on the long arm of chromosome 21. Our analysis of this locus indicated the presence of three VNTR systems. We estimated the heterozygosity of each system and sequenced one of the repetitive regions. Utilizing PCR, we demonstrated that the sequenced VNTR is responsible for the system with the highest level of heterozygosity. Combining data from the three systems makes D21S112 one of the most informative loci on the chromosome.

Original languageEnglish (US)
Pages (from-to)816-817
Number of pages2
JournalGenomics
Volume14
Issue number3
DOIs
StatePublished - Nov 1992
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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