Characterization of Compensatory Stepping in People with Multiple Sclerosis

Daniel Peterson, Jessie M. Huisinga, Rebecca I. Spain, Fay B. Horak

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective To characterize postural responses to forward and backward external perturbations in people with multiple sclerosis (PwMS), and to relate performance to commonly used clinical outcomes. Design Cross-sectional study. Postural responses were tested during large stepping and smaller feet-in-place perturbations in forward and backward directions. Setting University research laboratory. Participants PwMS (n=54) and age-matched controls (n=21) (N=75). Interventions Not applicable. Main Outcome Measures Center of mass displacement and step latency after external perturbations. Results PwMS exhibited larger center of mass displacements and step latencies than control participants in response to stepping perturbations (P=.003 and P=.028, respectively). Stepping deficits were more pronounced during backward stepping and were significantly correlated to increased severity on clinical measures (European Database for Multiple Sclerosis disability score and Timed 25-Foot Walk). Conclusions Compensatory stepping is impaired in PwMS and correlates with clinical disability. Measurement of backward compensatory stepping may be more effective at identifying postural dysfunction in PwMS than forward compensatory steps. Prolonged step latencies, large anticipatory postural adjustments, and multiple compensatory steps are especially altered in PwMS, suggesting possible targets for neurorehabilitation.

Original languageEnglish (US)
Pages (from-to)513-521
Number of pages9
JournalArchives of Physical Medicine and Rehabilitation
Volume97
Issue number4
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

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Multiple Sclerosis
Foot
Cross-Sectional Studies
Outcome Assessment (Health Care)
Databases
Research

Keywords

  • Accidental falls
  • Multiple sclerosis
  • Posture
  • Rehabilitation

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Characterization of Compensatory Stepping in People with Multiple Sclerosis. / Peterson, Daniel; Huisinga, Jessie M.; Spain, Rebecca I.; Horak, Fay B.

In: Archives of Physical Medicine and Rehabilitation, Vol. 97, No. 4, 01.04.2016, p. 513-521.

Research output: Contribution to journalArticle

Peterson, Daniel ; Huisinga, Jessie M. ; Spain, Rebecca I. ; Horak, Fay B. / Characterization of Compensatory Stepping in People with Multiple Sclerosis. In: Archives of Physical Medicine and Rehabilitation. 2016 ; Vol. 97, No. 4. pp. 513-521.
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