Characterization of a high-Q in-liquid longitudinal-mode film bulk acoustic resonator for real-time in-situ monitoring of competitive protein adsorption

Seokheun Choi, Wencheng Xu, Xu Zhang, Junseok Chae

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

We report the characterization results of in-liquid longitudinal-mode FBAR (L-FBAR) for real-time in-situ monitoring of the Vroman effect, a competitive adsorption and exchange of proteins on a surface. The change of resonant frequency of the L-FBAR, -1.55 GHz, is a direct function of the proteins' molecular weight, and thus we monitor the resonant frequency shifts to estimate the adsorption and exchange behavior. A low molecular weight (LMW) protein, albumin, initially covers the surface and is displaced by a high molecular weight (HMW) protein, IgG; sequentially, the highest molecular weight protein, fibrinogen displaces IgG. However, the reverse sequence does not occur.

Original languageEnglish (US)
Title of host publicationMEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest
Pages739-742
Number of pages4
DOIs
StatePublished - Jun 1 2010
Event23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 - Hong Kong, China
Duration: Jan 24 2010Jan 28 2010

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

Other23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
CountryChina
CityHong Kong
Period1/24/101/28/10

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Characterization of a high-Q in-liquid longitudinal-mode film bulk acoustic resonator for real-time in-situ monitoring of competitive protein adsorption'. Together they form a unique fingerprint.

  • Cite this

    Choi, S., Xu, W., Zhang, X., & Chae, J. (2010). Characterization of a high-Q in-liquid longitudinal-mode film bulk acoustic resonator for real-time in-situ monitoring of competitive protein adsorption. In MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest (pp. 739-742). [5442302] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2010.5442302