Characteristics of thalamic multi-unit activity and EEG during recovery from asphyxia

Jitendran Muthuswamy, Johnny K T Chao, David Sherman, Nitish V. Thakor

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Rhythmic cortical activity has been shown to have thalamic origin during high voltage spindles in some awake immobile rats. It was also found that EEG showed burst suppression patterns during recovery from a hypoxic/asphyxic insult to the brain. These have been shown to be prognostic of the neurological outcome after the injury. Some of these EEG burst patterns were rhythmic. Therefore, it was hypothesized that these rhythmic patterns also had a thalamic origin. Adult male Wistar rats (n=5) under Sodium Pentobarbital anesthesia were made to undergo a three minute period of asphyxia and then resuscitated. Extra-cellular activity from the ventral posterior medial nucleus was monitored. Cortical EEG was monitored bilaterally over the parietal region. Early recovery period in 4 of the 5 animals was characterized by episodes of sustained periodic discharges in the thalamus which correlated with periodic activity in the EEG. Thus, preliminary evidence indicates thalamic origins for the rhythmic EEG burst patterns observed during recovery from an asphyxic injury.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Pages2149-2150
Number of pages2
Volume5
StatePublished - 1997
Externally publishedYes
EventProceedings of the 1997 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Chicago, IL, USA
Duration: Oct 30 1997Nov 2 1997

Other

OtherProceedings of the 1997 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityChicago, IL, USA
Period10/30/9711/2/97

Fingerprint

Electroencephalography
Recovery
Rats
Pentobarbital
Brain
Animals
Sodium
Electric potential

ASJC Scopus subject areas

  • Bioengineering

Cite this

Muthuswamy, J., Chao, J. K. T., Sherman, D., & Thakor, N. V. (1997). Characteristics of thalamic multi-unit activity and EEG during recovery from asphyxia. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 5, pp. 2149-2150). IEEE.

Characteristics of thalamic multi-unit activity and EEG during recovery from asphyxia. / Muthuswamy, Jitendran; Chao, Johnny K T; Sherman, David; Thakor, Nitish V.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 5 IEEE, 1997. p. 2149-2150.

Research output: Chapter in Book/Report/Conference proceedingChapter

Muthuswamy, J, Chao, JKT, Sherman, D & Thakor, NV 1997, Characteristics of thalamic multi-unit activity and EEG during recovery from asphyxia. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 5, IEEE, pp. 2149-2150, Proceedings of the 1997 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, USA, 10/30/97.
Muthuswamy J, Chao JKT, Sherman D, Thakor NV. Characteristics of thalamic multi-unit activity and EEG during recovery from asphyxia. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 5. IEEE. 1997. p. 2149-2150
Muthuswamy, Jitendran ; Chao, Johnny K T ; Sherman, David ; Thakor, Nitish V. / Characteristics of thalamic multi-unit activity and EEG during recovery from asphyxia. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 5 IEEE, 1997. pp. 2149-2150
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