Central scars in primary liver tumors

MR features, specificity, and pathological correlation

E. Rummeny, R. Weissleder, S. Sironi, D. D. Stark, Carolyn Compton, P. F. Hahn, S. Saini, J. Wittenberg, J. T. Ferrucci

Research output: Contribution to journalArticle

99 Citations (Scopus)

Abstract

Tumor scars were identified at pathologic study and magnetic resonance (MR) imaging in ten of 17 (59%) primary liver tumors (nine hepatocellular carcinomas, four giant hemangiomas, two hepatic adenomas, and two cases of focal nodular hyperplasia). Histopathologic examination revealed three types of scar tissue. Inflammatory scars (n = 4), with edema, necrosis, hypercellularity, and loose fibrous tissue, appeared hypointense relative to liver on T1-weighted images and hyperintense of T2-weighted images. Vascular scars (n = 3), predominantly composed of vascular channels traversing collagenous tissue, showed MR features similar to those of inflammatory scars. Collagenous scars (n = 3) appeared hypointense relative to liver on both T1-weighted and T2-weighted images. Central tumor scars are a frequent but nonspecific feature of both benign and malignant primary liver tumors.

Original languageEnglish (US)
Pages (from-to)323-326
Number of pages4
JournalRadiology
Volume171
Issue number2
StatePublished - 1989
Externally publishedYes

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Cicatrix
Magnetic Resonance Spectroscopy
Liver
Neoplasms
Blood Vessels
Focal Nodular Hyperplasia
Hemangioma
Adenoma
Hepatocellular Carcinoma
Edema
Necrosis
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Rummeny, E., Weissleder, R., Sironi, S., Stark, D. D., Compton, C., Hahn, P. F., ... Ferrucci, J. T. (1989). Central scars in primary liver tumors: MR features, specificity, and pathological correlation. Radiology, 171(2), 323-326.

Central scars in primary liver tumors : MR features, specificity, and pathological correlation. / Rummeny, E.; Weissleder, R.; Sironi, S.; Stark, D. D.; Compton, Carolyn; Hahn, P. F.; Saini, S.; Wittenberg, J.; Ferrucci, J. T.

In: Radiology, Vol. 171, No. 2, 1989, p. 323-326.

Research output: Contribution to journalArticle

Rummeny, E, Weissleder, R, Sironi, S, Stark, DD, Compton, C, Hahn, PF, Saini, S, Wittenberg, J & Ferrucci, JT 1989, 'Central scars in primary liver tumors: MR features, specificity, and pathological correlation', Radiology, vol. 171, no. 2, pp. 323-326.
Rummeny E, Weissleder R, Sironi S, Stark DD, Compton C, Hahn PF et al. Central scars in primary liver tumors: MR features, specificity, and pathological correlation. Radiology. 1989;171(2):323-326.
Rummeny, E. ; Weissleder, R. ; Sironi, S. ; Stark, D. D. ; Compton, Carolyn ; Hahn, P. F. ; Saini, S. ; Wittenberg, J. ; Ferrucci, J. T. / Central scars in primary liver tumors : MR features, specificity, and pathological correlation. In: Radiology. 1989 ; Vol. 171, No. 2. pp. 323-326.
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