Cellular functionality on nanotubes of Ti-30Ta alloy

Patricia Capellato, Barbara Smith, Ketul C. Popat, Ana P R Alves Claro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Recent studies have identified strong correlations between anodized metals and the production of highly biomimetic nanoscale topographies. These surfaces provide an interface of enhanced biocompatibility that exhibits a high degree of oxidation and surface energy. In this study, Human dermal fibroblasts (HDF, neonatal) were utilized to evaluate the biocompatibility of Ti-30Ta nanotubes after 1 day of culture. The anodization process was performed in an electrolyte solution containing HF (48%) and H2SO4 (98%) in the volumetric ratios 1:9 with the addition of 5% dimethyl sulfoxide (DMSO) at 35V for 40 min. Cellular analysis identified improved fibroblast functionality on the nanotube surface, showing increased elongation, and extracellular matrix production on the Ti-30Ta nanotubes. The results presented identify improved cellular interaction on Ti-30Ta nanotubes as compared to the control substrates. Thus, the formation of the nanotube on Ti30Ta alloy may have potential application as interface for implantable devices.

Publication series

NameMaterials Science Forum
Volume805
ISSN (Print)02555476

Other

Other56 Brazilian Ceramic Conference, COLAOB 2012, Latin American Cong. of Artificial Organs and Biomaterials, 2012, 7th International Conference on Intelligent Processing and Manufacturing of Materials, IPMM, 2012, Brazilian Surface Treatments and Exhibition, EBRATS 2012, Ptech - 8th International Latin American Conference on Powder Technology, 2011
CountryBrazil
CityFoz de Iguaçu
Period9/2/129/3/12

Fingerprint

Nanotubes
nanotubes
fibroblasts
biocompatibility
Fibroblasts
Biocompatibility
Dimethyl sulfoxide
biomimetics
Biomimetics
Dimethyl Sulfoxide
Interfacial energy
Topography
Electrolytes
elongation
surface energy
Elongation
topography
Metals
electrolytes
Oxidation

Keywords

  • Human dermal fibroblasts
  • Ti-30Ta nanotube arrays

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering
  • Mechanics of Materials

Cite this

Capellato, P., Smith, B., Popat, K. C., & Alves Claro, A. P. R. (2015). Cellular functionality on nanotubes of Ti-30Ta alloy. In A Special Issue in Memory of Dr. Lucio Salgado (Vol. 805, pp. 61-64). (Materials Science Forum; Vol. 805). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/MSF.805.61

Cellular functionality on nanotubes of Ti-30Ta alloy. / Capellato, Patricia; Smith, Barbara; Popat, Ketul C.; Alves Claro, Ana P R.

A Special Issue in Memory of Dr. Lucio Salgado. Vol. 805 Trans Tech Publications Ltd, 2015. p. 61-64 (Materials Science Forum; Vol. 805).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Capellato, P, Smith, B, Popat, KC & Alves Claro, APR 2015, Cellular functionality on nanotubes of Ti-30Ta alloy. in A Special Issue in Memory of Dr. Lucio Salgado. vol. 805, Materials Science Forum, vol. 805, Trans Tech Publications Ltd, pp. 61-64, 56 Brazilian Ceramic Conference, COLAOB 2012, Latin American Cong. of Artificial Organs and Biomaterials, 2012, 7th International Conference on Intelligent Processing and Manufacturing of Materials, IPMM, 2012, Brazilian Surface Treatments and Exhibition, EBRATS 2012, Ptech - 8th International Latin American Conference on Powder Technology, 2011, Foz de Iguaçu, Brazil, 9/2/12. https://doi.org/10.4028/www.scientific.net/MSF.805.61
Capellato P, Smith B, Popat KC, Alves Claro APR. Cellular functionality on nanotubes of Ti-30Ta alloy. In A Special Issue in Memory of Dr. Lucio Salgado. Vol. 805. Trans Tech Publications Ltd. 2015. p. 61-64. (Materials Science Forum). https://doi.org/10.4028/www.scientific.net/MSF.805.61
Capellato, Patricia ; Smith, Barbara ; Popat, Ketul C. ; Alves Claro, Ana P R. / Cellular functionality on nanotubes of Ti-30Ta alloy. A Special Issue in Memory of Dr. Lucio Salgado. Vol. 805 Trans Tech Publications Ltd, 2015. pp. 61-64 (Materials Science Forum).
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