Abstract
A study was conducted to report the observations and systematic investigations of mercaptopropionic-acid-functionalized quantum dots (MPA-QD) into nuclei in the presence of a nuclear staining agent,4',6-diamidino-2- phenylindole (DAPI) and ultraviolet (UV) excitation. The study involved the culture of human cancer cells in the presence of green or red MPA-QDs, or incubated with antibody conjugated green QDs. The cells were also stained by DAPI,an organic dye specific for staining nuclei before imaging by fluorescence microscopy. It was observed that both green and red MPA-QDs are taken up into the the cytoplasm of live cells. It was also observed that the green MPA-QDs can move rapidly from the cytoplasm into nuclei in the presence of DAPI after UV excitation.
Original language | English (US) |
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Pages (from-to) | 3468-3473 |
Number of pages | 6 |
Journal | Advanced Materials |
Volume | 20 |
Issue number | 18 |
DOIs | |
State | Published - Sep 17 2008 |
ASJC Scopus subject areas
- General Materials Science
- Mechanics of Materials
- Mechanical Engineering