Catalysis by the RNA subunit of RNase P - a minireview

S. Altman, M. F. Baer, M. Bartkiewicz, H. Gold, C. Guerrier-Takada, L. A. Kirsebom, N. Lumelsky, K. Peck

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

RNase P, an enzyme that contains both RNA and protein components, cleaves tRNA precursors to generate mature 5′ termini. The catalytic activity of RNase P resides in the RNA component, with the protein cofactor affecting the rate of the cleavage reaction. The reaction is also influenced by the nature of the tRNA substrate.

Original languageEnglish (US)
Pages (from-to)63-64
Number of pages2
JournalGene
Volume82
Issue number1
DOIs
StatePublished - Oct 15 1989
Externally publishedYes

Keywords

  • Catalytic RNA
  • M1 RNA structure and function
  • model substrates
  • nucleotide sequences
  • protein cofactor

ASJC Scopus subject areas

  • Genetics

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  • Cite this

    Altman, S., Baer, M. F., Bartkiewicz, M., Gold, H., Guerrier-Takada, C., Kirsebom, L. A., Lumelsky, N., & Peck, K. (1989). Catalysis by the RNA subunit of RNase P - a minireview. Gene, 82(1), 63-64. https://doi.org/10.1016/0378-1119(89)90030-9