TY - JOUR
T1 - Building Global Genomics Initiatives and Enabling Data Sharing
T2 - Insights from Multiple Case Studies
AU - Fusi, Federica
AU - Manzella, Daniele
AU - Louafi, Selim
AU - Welch, Eric
N1 - Funding Information:
This research was made possible through generous support by the United Nations Food and Agriculture Organization and the Global Crop Diversity Trust. Selim Louafi’s has been supported by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under the Research Executive agency (REA) grant agreement no. 628785. The authors also acknowledge the anonymous reviewers for their helpful comments and suggestions.
Funding Information:
API, application programming interface; IT, information technology; NSF, National Science Foundation.
Funding Information:
API = application programming interface IT = information technology NSF = National Science Foundation R&D = research and development
Funding Information:
A search for sustainable models. We found that no initiative has a concrete well-defined solution to secure funding stability over time. The resources are either developed through grant funding involving public or nonprofit funders, such as National Science Foundation, Wellcome Trust, and the Gates Foundation, or mobilized through voluntary contributions from the community. But the financial model varies across cases, with some initiatives that are entirely publicly funded to others that rely heavily on the voluntary contribution of member time and resources.
Publisher Copyright:
© 2018, Mary Ann Liebert, Inc.
PY - 2018/4
Y1 - 2018/4
N2 - This genomics global governance research study presents the dynamics and the evolving nature of salient challenges that global genomics initiatives encounter in designing new models for data management, exchange, and collaboration across disciplines, sectors, and countries. Using a multiple case study approach, we assessed and compared organizational responses across diverse genomics initiatives. The richness of a comparative qualitative analysis clearly shows the complexity addressed by genomics initiatives and, importantly, expands current studies by moving beyond an open versus property regime dichotomy. Although we identify some common themes, fundamental differences emerge in the way genomics initiatives set goals, manage heterogeneity, define resources, devise governance, and enable data sharing. Such differences demonstrate the ongoing processes of adapting governance structures, management processes, and organizational design solutions that are implemented in response to different social, technical, and policy environments. We find that genomics initiatives largely benefit from and are shaped by the engagement with large communities of scientists to rethink and design shared rules and guidelines for data exchange and use. Our study provides direct guidance to future global genomics initiatives, but it also offers a benchmark for research in the omics field broadly, both in terms of design and methodological approaches to understand the emerging forms of scientific governance and innovation ecosystems.
AB - This genomics global governance research study presents the dynamics and the evolving nature of salient challenges that global genomics initiatives encounter in designing new models for data management, exchange, and collaboration across disciplines, sectors, and countries. Using a multiple case study approach, we assessed and compared organizational responses across diverse genomics initiatives. The richness of a comparative qualitative analysis clearly shows the complexity addressed by genomics initiatives and, importantly, expands current studies by moving beyond an open versus property regime dichotomy. Although we identify some common themes, fundamental differences emerge in the way genomics initiatives set goals, manage heterogeneity, define resources, devise governance, and enable data sharing. Such differences demonstrate the ongoing processes of adapting governance structures, management processes, and organizational design solutions that are implemented in response to different social, technical, and policy environments. We find that genomics initiatives largely benefit from and are shaped by the engagement with large communities of scientists to rethink and design shared rules and guidelines for data exchange and use. Our study provides direct guidance to future global genomics initiatives, but it also offers a benchmark for research in the omics field broadly, both in terms of design and methodological approaches to understand the emerging forms of scientific governance and innovation ecosystems.
KW - case study
KW - data sharing
KW - global genomics initiatives
KW - global governance innovation
KW - organizational design
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U2 - 10.1089/omi.2017.0214
DO - 10.1089/omi.2017.0214
M3 - Article
C2 - 29584582
AN - SCOPUS:85045426350
SN - 1536-2310
VL - 22
SP - 237
EP - 247
JO - OMICS A Journal of Integrative Biology
JF - OMICS A Journal of Integrative Biology
IS - 4
ER -