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Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model
T. A. Brandt,
Bertram Jacobs
Immunotherapy, Vaccines and Virotherapy, Center for (CIVV)
Life Sciences, School of (SOLS)
Research output
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Contribution to journal
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Article
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peer-review
172
Scopus citations
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Agriculture & Biology
Vaccinia virus
100%
interferons
86%
pathogenesis
69%
resistance genes
67%
animal models
66%
cell culture
45%
double-stranded RNA
41%
infection
40%
morbidity
39%
host range
36%
weight loss
32%
Orthopoxvirus
29%
genes
19%
lethal dose 50
19%
protein kinases
18%
death
14%
injection
13%
viruses
12%
animals
7%
Medicine & Life Sciences
Vaccinia virus
90%
Interferons
69%
eIF-2 Kinase
54%
Host Specificity
47%
Double-Stranded RNA
45%
Cell Culture Techniques
43%
Infections
36%
Weight Loss
31%
Genes
30%
Orthopoxvirus
29%
Morbidity
22%
Lethal Dose 50
21%
Antiviral Agents
16%
Viruses
12%
Injections
10%
Animals
9%