Abstract
Mild cognitive impairment (MCI) is an intermediate stage between normal aging and Alzheimer's disease (AD), and around 10-15% of people with MCI develop AD each year. More recently, MCI has been further subdivided into early and late stages, and there is interest in identifying sensitive brain imaging biomarkers that help to differentiate stages of MCI. Here, we focused on anatomical brain networks computed from diffusion MRI and proposed a new feature extraction and classification framework based on higher order singular value decomposition and sparse logistic regression. In tests on publicly available data from the Alzheimer's Disease Neuroimaging Initiative, our proposed framework showed promise in detecting brain network differences that help in classifying early versus late MCI.
Original language | English (US) |
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Title of host publication | 2015 IEEE 12th International Symposium on Biomedical Imaging, ISBI 2015 |
Publisher | IEEE Computer Society |
Pages | 131-135 |
Number of pages | 5 |
ISBN (Electronic) | 9781479923748 |
DOIs | |
State | Published - Jul 21 2015 |
Externally published | Yes |
Event | 12th IEEE International Symposium on Biomedical Imaging, ISBI 2015 - Brooklyn, United States Duration: Apr 16 2015 → Apr 19 2015 |
Publication series
Name | Proceedings - International Symposium on Biomedical Imaging |
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Volume | 2015-July |
ISSN (Print) | 1945-7928 |
ISSN (Electronic) | 1945-8452 |
Other
Other | 12th IEEE International Symposium on Biomedical Imaging, ISBI 2015 |
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Country/Territory | United States |
City | Brooklyn |
Period | 4/16/15 → 4/19/15 |
Keywords
- Mild Cognitive Impairment
- brain network
- classification
- diffusion MRI
- high order SVD
ASJC Scopus subject areas
- Biomedical Engineering
- Radiology Nuclear Medicine and imaging