Biomolecular interaction analysis mass spectrometry: A comprehensive microscale proteomics approach

Dobrin Nedelkov, Randall W. Nelson

Research output: Contribution to journalArticle

Abstract

Biomolecular interaction analysis mass spectrometry (BIA-MS) is a comprehensive microscale proteomics approach. The chip platform is an ideal podium for protein characterization, in parallel with the plethora of DNA/RNA chips that became a mainstay in the study of the human genome. The combination of SPR sensing and the mass selective detection of MALDI-TOF MS makes BIA-MS an important tool for characterizing proteins from their native environment.

Original languageEnglish (US)
Pages (from-to)22-25
Number of pages4
JournalAmerican Laboratory
Volume33
Issue number12
StatePublished - Jun 2001

ASJC Scopus subject areas

  • Analytical Chemistry
  • Instrumentation

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