Biomarkers for establishing a tolerable upper intake level for vitamin C

Research output: Contribution to journalReview articlepeer-review

59 Scopus citations

Abstract

Dietary reference intakes (DRIs) for vitamin C for healthy U.S. populations are currently being formulated by the Panel on Dietary Antioxidants and Related Compounds of the Food and Nutrition Board of the Institute of Medicine. A major task of the Panel is to analyze the evidence of adverse effects of high-dose vitamin C intakes to derive, if appropriate, a Tolerable Upper Intake Level (UL) for vitamin C. The present report details current and past research examining potential adverse effects of supplemental vitamin C. The available data indicate that very high intakes of vitamin C (2-4 g/day) are well tolerated biologically in healthy mammalian systems. Currently, strong scientific evidence to define and defend a UL for vitamin C is not available.

Original languageEnglish (US)
Pages (from-to)71-77
Number of pages7
JournalNutrition Reviews
Volume57
Issue number3
DOIs
StatePublished - Mar 1999

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Fingerprint Dive into the research topics of 'Biomarkers for establishing a tolerable upper intake level for vitamin C'. Together they form a unique fingerprint.

Cite this