@inproceedings{76ce466ce0ca44d68a74c2c1a8d60d8c,
title = "Biological circuit models of immune regulatory response: A decentralized control system",
abstract = "The purpose of this paper is to present a model of immune control based on recently discovered regulatory properties of the immune system. The immune system is a control system which self optimizes over time to eliminate disease while avoiding harm to the host. The controller acts without centralized authority. Recent research has revealed new T-cell populations involved in regulating the immune response. We show how interactions of these populations at the cellular level can give rise to population dynamics which mimic a PID controller with on/off switching. We study these nonlinear dynamics and show stability using Lyapunov analysis. We also include the results of simulation.",
author = "Matthew Peet and Peter Kim and Lee, {Peter P.}",
year = "2011",
doi = "10.1109/CDC.2011.6161395",
language = "English (US)",
isbn = "9781612848006",
series = "Proceedings of the IEEE Conference on Decision and Control",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "3020--3025",
booktitle = "2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011",
note = "2011 50th IEEE Conference on Decision and Control and European Control Conference, CDC-ECC 2011 ; Conference date: 12-12-2011 Through 15-12-2011",
}