Biofilms and the plasmid maintenance question

Mudassar Imran, Donald Jones, Hal Smith

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.

Original languageEnglish (US)
Pages (from-to)183-204
Number of pages22
JournalMathematical Biosciences
Volume193
Issue number2
DOIs
StatePublished - Feb 2005

Fingerprint

Chemostats
Biofilm
Biofilms
plasmid
biofilm
plasmids
Maintenance
Plasmids
Mathematical models
Chemostat
Computer simulation
Persistence
chemostat
Encoding
Mathematical Model
Numerical Simulation
Theoretical Models
mathematical models
persistence
Growth

Keywords

  • Bacterial wall growth
  • Biofilm
  • Chemostat
  • Conjugation
  • Model
  • Plasmid
  • Plug flow
  • Segregation

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Ecology, Evolution, Behavior and Systematics

Cite this

Biofilms and the plasmid maintenance question. / Imran, Mudassar; Jones, Donald; Smith, Hal.

In: Mathematical Biosciences, Vol. 193, No. 2, 02.2005, p. 183-204.

Research output: Contribution to journalArticle

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