Binge drinking in adolescence predicts an atypical cortisol stress response in young adulthood

Melissa J. Hagan, Kathryn Modecki, Lucy Moctezuma Tan, Linda Luecken, Sharlene Wolchik, Irwin Sandler

    Research output: Contribution to journalArticle

    Abstract

    Adolescence is a sensitive developmental period in which substance use can exert long-term effects on important biological systems. Emerging cross-sectional research indicates that problematic alcohol consumption may be associated with dysregulated neuroendocrine system functioning. The current study evaluated the prospective effects of binge drinking in adolescence on cortisol stress reactivity in young adulthood among individuals who had experienced parental divorce in childhood (N = 160; Mean age = 25.55, SD = 1.22; 46.9% Female; 88.8% White Non-Hispanic). Youth completed validated measures of problematic drinking during adolescence (aged 15–19) and participated in a standardized social stress task nine years later in young adulthood. Latent growth modeling was conducted within a structural equation modeling framework. Greater binge drinking during adolescence was associated with a significantly lower cortisol stress response in young adulthood, controlling for young adult drinking, sex, childhood externalizing problems, and socioeconomic status. Findings suggest problematic alcohol consumption during mid-to-late adolescence may have important effects on the neuroendocrine stress response system at subsequent developmental stages.

    Original languageEnglish (US)
    Pages (from-to)137-144
    Number of pages8
    JournalPsychoneuroendocrinology
    Volume100
    DOIs
    StatePublished - Feb 1 2019

    Fingerprint

    Binge Drinking
    Hydrocortisone
    Alcohol Drinking
    Drinking
    Neurosecretory Systems
    Divorce
    Social Class
    Young Adult
    Prospective Studies
    Growth
    Research

    Keywords

    • Adolescence
    • Alcohol
    • Binge drinking
    • Cortisol
    • Young adulthood

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Endocrinology
    • Endocrine and Autonomic Systems
    • Psychiatry and Mental health
    • Biological Psychiatry

    Cite this

    Binge drinking in adolescence predicts an atypical cortisol stress response in young adulthood. / Hagan, Melissa J.; Modecki, Kathryn; Moctezuma Tan, Lucy; Luecken, Linda; Wolchik, Sharlene; Sandler, Irwin.

    In: Psychoneuroendocrinology, Vol. 100, 01.02.2019, p. 137-144.

    Research output: Contribution to journalArticle

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