TY - GEN
T1 - Beta process based adaptive learning for immunosignature microarray feature identification
AU - Malin, Anna
AU - Kovvali, Narayan
AU - Papandreou-Suppappola, Antonia
AU - Zhang, Jun Jason
AU - Johnston, Stephen
AU - Stafford, Phillip
PY - 2012/12/1
Y1 - 2012/12/1
N2 - We propose a latent feature model for immunosignature random peptide microarray data using beta process factor analysis to identify relationships between patients and infectious agents. The method uses Bayesian nonparametric adaptive learning techniques that allow for further classification if additional patient data is received, and new relationships between patients and disease states are obtained. In addition to feature discovery, this methodology can also detect biothreat agents on the fly. Using experimental immunosignature microarray data, we demonstrate the identification and classification of underlying relationships between patients with different disease states.
AB - We propose a latent feature model for immunosignature random peptide microarray data using beta process factor analysis to identify relationships between patients and infectious agents. The method uses Bayesian nonparametric adaptive learning techniques that allow for further classification if additional patient data is received, and new relationships between patients and disease states are obtained. In addition to feature discovery, this methodology can also detect biothreat agents on the fly. Using experimental immunosignature microarray data, we demonstrate the identification and classification of underlying relationships between patients with different disease states.
UR - http://www.scopus.com/inward/record.url?scp=84876222222&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84876222222&partnerID=8YFLogxK
U2 - 10.1109/ACSSC.2012.6489312
DO - 10.1109/ACSSC.2012.6489312
M3 - Conference contribution
AN - SCOPUS:84876222222
SN - 9781467350518
T3 - Conference Record - Asilomar Conference on Signals, Systems and Computers
SP - 1651
EP - 1655
BT - Conference Record of the 46th Asilomar Conference on Signals, Systems and Computers, ASILOMAR 2012
T2 - 46th Asilomar Conference on Signals, Systems and Computers, ASILOMAR 2012
Y2 - 4 November 2012 through 7 November 2012
ER -