BAFfled by Poxviruses?

Research output: Contribution to journalShort survey

Abstract

Successful viruses engage in a dynamic interplay with their hosts, where both utilize diverse strategies to impose their supremacy. In this issue of Cell Host & Microbe, Wiebe and Traktman describe a novel interaction between vaccinia virus and mammalian cells. A host protein called BAF can bind ectopic cytoplasmic DNA and block viral DNA replication, whereas vaccinia in turn counteracts this inhibition with a virus-encoded serine threonine kinase that inactivates BAF.

Original languageEnglish (US)
Pages (from-to)159-160
Number of pages2
JournalCell Host and Microbe
Volume1
Issue number3
DOIs
StatePublished - May 17 2007
Externally publishedYes

Fingerprint

Poxviridae
Viruses
Vaccinia
Vaccinia virus
Protein-Serine-Threonine Kinases
Viral DNA
DNA Replication
DNA
Proteins

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

Cite this

BAFfled by Poxviruses? / Rahman, Masmudur; McFadden, Douglas.

In: Cell Host and Microbe, Vol. 1, No. 3, 17.05.2007, p. 159-160.

Research output: Contribution to journalShort survey

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