Abstract
Successful viruses engage in a dynamic interplay with their hosts, where both utilize diverse strategies to impose their supremacy. In this issue of Cell Host & Microbe, Wiebe and Traktman describe a novel interaction between vaccinia virus and mammalian cells. A host protein called BAF can bind ectopic cytoplasmic DNA and block viral DNA replication, whereas vaccinia in turn counteracts this inhibition with a virus-encoded serine threonine kinase that inactivates BAF.
Original language | English (US) |
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Pages (from-to) | 159-160 |
Number of pages | 2 |
Journal | Cell Host and Microbe |
Volume | 1 |
Issue number | 3 |
DOIs | |
State | Published - May 17 2007 |
Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Virology