Abstract
The equilibrium inbreeding is always higher than the average inbreeding. For human populations with high inbreeding levels, the inbreeding equilibrium is more than 25% higher than the average inbreeding. Assuming no initial inbreeding in the population, the equilibrium inbreeding value is closely approached in 10 generations or less. A secondary effect of this higher inbreeding level is that the equilibrium frequency of recessive detrimental alleles is somewhat lower than expected using average inbreeding.
Original language | English (US) |
---|---|
Pages (from-to) | 965-970 |
Number of pages | 6 |
Journal | American Journal of Human Genetics |
Volume | 38 |
Issue number | 6 |
State | Published - 1986 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)