Average inbreeding or equilibrium inbreeding?

P. W. Hedrick

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The equilibrium inbreeding is always higher than the average inbreeding. For human populations with high inbreeding levels, the inbreeding equilibrium is more than 25% higher than the average inbreeding. Assuming no initial inbreeding in the population, the equilibrium inbreeding value is closely approached in 10 generations or less. A secondary effect of this higher inbreeding level is that the equilibrium frequency of recessive detrimental alleles is somewhat lower than expected using average inbreeding.

Original languageEnglish (US)
Pages (from-to)965-970
Number of pages6
JournalAmerican Journal of Human Genetics
Volume38
Issue number6
StatePublished - Jan 1 1986

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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