Average heterozygosity revisited

P. W. Hedrick, E. Murray

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The estimate of heterozygosity and proportion of polymorphic loci for 33 red blood cell loci has been updated by the elimination of some loci of questionable status and the addition of data on 33 loci. The new figures for heterozygosity and proportion of polymorphic loci, .105 and .283, respectively, are based on 60 red blood cell loci of European origin populations. These values are less than those calculated by Lewontin in 1967, and furthermore they do not appear to be reaching an asymptote. At the present time, the red blood cell data and allozyme data for European populations have similar estimates of heterozygosity and proportion of polymorphic loci.

Original languageEnglish (US)
Pages (from-to)377-382
Number of pages6
JournalAmerican Journal of Human Genetics
Issue number4
StatePublished - 1978
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)


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