@article{054d0eb4aad44a149817a62b107dbc5d,
title = "Asthma and bronchial hyperresponsiveness linked to the XY long arm pseudoautosomal region",
abstract = "We examined the long arm XY pseudoautosomal region for linkage to asthma, serum IgE, and bronchial hyperresponsiveness. In 57 Caucasian families multipoint nonparametric analyses provide evidence for linkage between DXYS154 and bronchial hyperresponsiveness (P = 0.000057) or asthma (P = 0.00065). This genomic region is approximately 320 kb in size and contains the interleukin-9 receptor gene. These results suggest that a gene controlling asthma and bronchial hyperresponsiveness maybe located in this region and that the interleukin-9 receptor is a potential candidate.",
author = "Holroyd, {Kenneth J.} and Martinati, {Laura C.} and Elisabetta Trabetti and Titia Scherpbier and Eleff, {Scott M.} and Boner, {Attilio L.} and Pignatti, {Pier Franco} and Kiser, {Matthew B.} and Dragwa, {Carl R.} and Frank Hubbard and Sullivan, {Christine D.} and Luigi Grasso and Messler, {Carol J.} and Minxue Huang and Ying Hu and Nicolaides, {Nicholas C.} and Buetow, {Kenneth H.} and Levitt, {Roy C.}",
note = "Funding Information: Many thanks to Jean-Christophe Renauld and Jacques Van Snick for their advice and helpful suggestions. We also thank Anna B. Cassidy. Dr. Eleff is an established investigator of the American Heart Association. We gratefully acknowledge the contribution made by each volunteer in this study. Kenneth H. Buetow is supported, in part, by Magainin Pharmaceuticals, Inc., Fox Chase Institutional Core Grant 5P30 CA06927-35 and 2P50 HG00835-05 supporting the Cooperative Human Linkage Center. P.F.P. gratefully acknowledges partial support from a Telethon Italy grant. The software packages used included SAGE, which is supported by a U.S. Public Health Service Resource grant (1 P41 RR03655) from the National Center for Research Resources.",
year = "1998",
month = sep,
day = "1",
doi = "10.1006/geno.1998.5445",
language = "English (US)",
volume = "52",
pages = "233--235",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "2",
}