Assignment of 22 loci in the rat by somatic hybrid and linkage analysis

Raymond S. Yeung; Okio Hino; Maria Vilensky; Kenneth Buetow; Claude Szpirer; Josiane Szpirer

doi:10.1007/BF00361389

Assignment of 22 loci in the rat by somatic hybrid and linkage analysis

Raymond S. Yeung, Okio Hino, Maria Vilensky, Kenneth Buetow, Claude Szpirer, Josiane Szpirer

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Twenty structural genes and two unique anonymous DNA fragments have been mapped in the rat (Rattus norvegicus) with a panel of mouse x rat hybrids and linkage analysis. Ten of the 20 autosomes are represented by at least one of these markers. A new syntenic relationship among rat Chromosome (Chr) 16, mouse Chr 14, and human Chr 10q was established. Results of this study further support the extensive conservation of syntheny between the rat and mouse and, to a lesser degree, between rat and human.

Original language	English (US)
Pages (from-to)	585-588
Number of pages	4
Journal	Mammalian Genome
Volume	4
Issue number	10
DOIs	https://doi.org/10.1007/BF00361389
State	Published - Oct 1993
Externally published	Yes

ASJC Scopus subject areas

Genetics

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AU - Yeung, Raymond S.

AU - Hino, Okio

AU - Vilensky, Maria

AU - Buetow, Kenneth

AU - Szpirer, Claude

AU - Szpirer, Josiane

PY - 1993/10

Y1 - 1993/10

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AB - Twenty structural genes and two unique anonymous DNA fragments have been mapped in the rat (Rattus norvegicus) with a panel of mouse x rat hybrids and linkage analysis. Ten of the 20 autosomes are represented by at least one of these markers. A new syntenic relationship among rat Chromosome (Chr) 16, mouse Chr 14, and human Chr 10q was established. Results of this study further support the extensive conservation of syntheny between the rat and mouse and, to a lesser degree, between rat and human.

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Assignment of 22 loci in the rat by somatic hybrid and linkage analysis

Abstract

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