Assignment of 22 loci in the rat by somatic hybrid and linkage analysis

Raymond S. Yeung, Okio Hino, Maria Vilensky, Kenneth Buetow, Claude Szpirer, Josiane Szpirer

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Twenty structural genes and two unique anonymous DNA fragments have been mapped in the rat (Rattus norvegicus) with a panel of mouse x rat hybrids and linkage analysis. Ten of the 20 autosomes are represented by at least one of these markers. A new syntenic relationship among rat Chromosome (Chr) 16, mouse Chr 14, and human Chr 10q was established. Results of this study further support the extensive conservation of syntheny between the rat and mouse and, to a lesser degree, between rat and human.

Original languageEnglish (US)
Pages (from-to)585-588
Number of pages4
JournalMammalian Genome
Volume4
Issue number10
DOIs
StatePublished - Oct 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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    Yeung, R. S., Hino, O., Vilensky, M., Buetow, K., Szpirer, C., & Szpirer, J. (1993). Assignment of 22 loci in the rat by somatic hybrid and linkage analysis. Mammalian Genome, 4(10), 585-588. https://doi.org/10.1007/BF00361389