Assessing the Potential to Monitor Plant-Based Diet Trends in Communities Using a Wastewater-Based Epidemiology Approach

Arjun K. Venkatesan, Jing Chen, Erin Driver, Adam Gushgari, Rolf Halden

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

With the successful demonstration of wastewater-based epidemiology (WBE) approaches in different countries for estimating the consumption of illicit drugs, researchers are convinced of the approach's potential to include other biomarkers of exposures to complement and expand traditional human biomonitoring efforts. To this end, for the first time, the present study tested the potential to monitor plant-based diet trends in two U.S. cities by measuring levels of phytoestrogens (plant-derived human biomarkers) in influent wastewater. We analyzed monthly samples (2015-2016) of raw wastewater from two midwestern U.S. cities using liquid chromatography-tandem mass spectrometry for three phytoestrogens: daidzein, genistein, and enterolactone. Phytoestrogens were detected in 100% (n = 23) of the samples analyzed, and the concentrations (ng/L) in raw wastewater from Cities 1 and 2, respectively, in decreasing abundance were: enterolactone at 931 ± 267 and 1016 ± 439; daidzein at 821 ± 208 and 783 ± 371; and genistein at 253 ± 90 and 174 ± 83. The relative abundance of phytoestrogens detected in wastewater mirrored their previously reported relative abundance in human urine and is in agreement with the typical plant-based diet (rich in lignans) consumed in the United States. Average phytoestrogen consumption estimated using the WBE approach ranged between 94 and 645 μg/d/capita for these compounds, with City 2 exhibiting higher plant-based consumption than City 1. These estimates were in agreement with consumption values calculated from the previously reported urinary concentration of phytoestrogen for the U.S. population. The present study showed that phytoestrogen are ideal WBE biomarkers to study plant-based diet trends in communities, provided that there is no industrial input of phytoestrogens entering the sewershed.

Original languageEnglish (US)
Title of host publicationWastewater-Based Epidemiology
Subtitle of host publicationEstimation of Community Consumption of Drugs and Diets
EditorsDaniel A. Burgard, Bikram Subedi, Bommanna G. Loganathan
PublisherAmerican Chemical Society
Pages187-198
Number of pages12
ISBN (Electronic)9780841234413
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Publication series

NameACS Symposium Series
Volume1319
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

Fingerprint

Phytoestrogens
Epidemiology
Nutrition
Wastewater
Biomarkers
Genistein
Liquid chromatography
Lignans
Street Drugs
Mass spectrometry
Demonstrations

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Venkatesan, A. K., Chen, J., Driver, E., Gushgari, A., & Halden, R. (2019). Assessing the Potential to Monitor Plant-Based Diet Trends in Communities Using a Wastewater-Based Epidemiology Approach. In D. A. Burgard, B. Subedi, & B. G. Loganathan (Eds.), Wastewater-Based Epidemiology: Estimation of Community Consumption of Drugs and Diets (pp. 187-198). (ACS Symposium Series; Vol. 1319). American Chemical Society. https://doi.org/10.1021/bk-2019-1319.ch010

Assessing the Potential to Monitor Plant-Based Diet Trends in Communities Using a Wastewater-Based Epidemiology Approach. / Venkatesan, Arjun K.; Chen, Jing; Driver, Erin; Gushgari, Adam; Halden, Rolf.

Wastewater-Based Epidemiology: Estimation of Community Consumption of Drugs and Diets. ed. / Daniel A. Burgard; Bikram Subedi; Bommanna G. Loganathan. American Chemical Society, 2019. p. 187-198 (ACS Symposium Series; Vol. 1319).

Research output: Chapter in Book/Report/Conference proceedingChapter

Venkatesan, AK, Chen, J, Driver, E, Gushgari, A & Halden, R 2019, Assessing the Potential to Monitor Plant-Based Diet Trends in Communities Using a Wastewater-Based Epidemiology Approach. in DA Burgard, B Subedi & BG Loganathan (eds), Wastewater-Based Epidemiology: Estimation of Community Consumption of Drugs and Diets. ACS Symposium Series, vol. 1319, American Chemical Society, pp. 187-198. https://doi.org/10.1021/bk-2019-1319.ch010
Venkatesan AK, Chen J, Driver E, Gushgari A, Halden R. Assessing the Potential to Monitor Plant-Based Diet Trends in Communities Using a Wastewater-Based Epidemiology Approach. In Burgard DA, Subedi B, Loganathan BG, editors, Wastewater-Based Epidemiology: Estimation of Community Consumption of Drugs and Diets. American Chemical Society. 2019. p. 187-198. (ACS Symposium Series). https://doi.org/10.1021/bk-2019-1319.ch010
Venkatesan, Arjun K. ; Chen, Jing ; Driver, Erin ; Gushgari, Adam ; Halden, Rolf. / Assessing the Potential to Monitor Plant-Based Diet Trends in Communities Using a Wastewater-Based Epidemiology Approach. Wastewater-Based Epidemiology: Estimation of Community Consumption of Drugs and Diets. editor / Daniel A. Burgard ; Bikram Subedi ; Bommanna G. Loganathan. American Chemical Society, 2019. pp. 187-198 (ACS Symposium Series).
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