TY - JOUR
T1 - Assessing the need for a standardized cancer Human Biobank (caHUB)
T2 - Findings from a national survey with cancer researchers
AU - Massett, Holly A.
AU - Atkinson, Nancy L.
AU - Weber, Deanne
AU - Myles, Renate
AU - Ryan, Colleen
AU - Grady, Meredith
AU - Compton, Carolyn
PY - 2011
Y1 - 2011
N2 - Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.
AB - Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.
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U2 - 10.1093/jncimonographs/lgr007
DO - 10.1093/jncimonographs/lgr007
M3 - Article
C2 - 21672890
AN - SCOPUS:80053418647
SN - 1052-6773
SP - 8
EP - 15
JO - Journal of the National Cancer Institute - Monographs
JF - Journal of the National Cancer Institute - Monographs
IS - 42
ER -