Assessing the need for a standardized cancer Human Biobank (caHUB): Findings from a national survey with cancer researchers

Holly A. Massett, Nancy L. Atkinson, Deanne Weber, Renate Myles, Colleen Ryan, Meredith Grady, Carolyn Compton

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.

Original languageEnglish (US)
Pages (from-to)8-15
Number of pages8
JournalJournal of the National Cancer Institute. Monographs
Issue number42
DOIs
StatePublished - 2011
Externally publishedYes

Fingerprint

Research Personnel
National Cancer Institute (U.S.)
Neoplasms
Research
Surveys and Questionnaires

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

Cite this

Assessing the need for a standardized cancer Human Biobank (caHUB) : Findings from a national survey with cancer researchers. / Massett, Holly A.; Atkinson, Nancy L.; Weber, Deanne; Myles, Renate; Ryan, Colleen; Grady, Meredith; Compton, Carolyn.

In: Journal of the National Cancer Institute. Monographs, No. 42, 2011, p. 8-15.

Research output: Contribution to journalArticle

Massett, Holly A. ; Atkinson, Nancy L. ; Weber, Deanne ; Myles, Renate ; Ryan, Colleen ; Grady, Meredith ; Compton, Carolyn. / Assessing the need for a standardized cancer Human Biobank (caHUB) : Findings from a national survey with cancer researchers. In: Journal of the National Cancer Institute. Monographs. 2011 ; No. 42. pp. 8-15.
@article{fb12502b74e5466587d762a637cc58e3,
title = "Assessing the need for a standardized cancer Human Biobank (caHUB): Findings from a national survey with cancer researchers",
abstract = "Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56{\%}) participants obtained biospecimens within their own institutions, and 63{\%} wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39{\%}) and quality (47{\%}). Low-quality biospecimens resulted in 60{\%} questioning their findings and 81{\%} limiting the scope of their work. Nine in every 10 (91.3{\%}) respondents reacted positively to the idea of a national biospecimen resource, with 62{\%} reporting that they would obtain biospecimens from it and 53{\%} reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.",
author = "Massett, {Holly A.} and Atkinson, {Nancy L.} and Deanne Weber and Renate Myles and Colleen Ryan and Meredith Grady and Carolyn Compton",
year = "2011",
doi = "10.1093/jncimonographs/lgr007",
language = "English (US)",
pages = "8--15",
journal = "NCI Monographs",
issn = "1052-6773",
publisher = "Oxford University Press",
number = "42",

}

TY - JOUR

T1 - Assessing the need for a standardized cancer Human Biobank (caHUB)

T2 - Findings from a national survey with cancer researchers

AU - Massett, Holly A.

AU - Atkinson, Nancy L.

AU - Weber, Deanne

AU - Myles, Renate

AU - Ryan, Colleen

AU - Grady, Meredith

AU - Compton, Carolyn

PY - 2011

Y1 - 2011

N2 - Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.

AB - Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.

UR - http://www.scopus.com/inward/record.url?scp=80053418647&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053418647&partnerID=8YFLogxK

U2 - 10.1093/jncimonographs/lgr007

DO - 10.1093/jncimonographs/lgr007

M3 - Article

C2 - 21672890

AN - SCOPUS:80053418647

SP - 8

EP - 15

JO - NCI Monographs

JF - NCI Monographs

SN - 1052-6773

IS - 42

ER -