Assessing Acceptability of Self-Sampling Kits, Prevalence, and Risk Factors for Human Papillomavirus Infection in American Indian Women

Rachel L. Winer, Angela Gonzales, Carolyn J. Noonan, Stephen L. Cherne, Dedra S. Buchwald, the Collaborative to Improve Native Cancer Outcomes (CINCO) for the Collaborative to Improve Native Cancer Outcomes (CINCO)

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We evaluated the feasibility and acceptability of self-sampling for human papillomavirus (HPV) testing and calculated the prevalence of and risk factors for high-risk (hr) HPV infections in a community-based sample of American Indian women. To this end, we recruited 329 Hopi women aged 21–65 years to self-collect vaginal samples for hrHPV testing. Samples were tested by polymerase chain reaction for 14 hrHPV genotypes. We used Chi square tests to identify correlates of preference for clinician Pap testing versus HPV self-sampling, and age-adjusted Poisson regression to evaluate correlates of hrHPV prevalence. We found that satisfaction with HPV self-sampling was high, with 96 % of women reporting that the sample was easy to collect and 87 % reporting no discomfort. The majority (62 %) indicated that they preferred HPV self-sampling to receiving a Pap test from a clinician. Preference for Pap testing over HPV self-sampling was positively associated with adherence to Pap screening and employment outside the home. All samples evaluated were satisfactory for HPV testing, and 22 % were positive for hrHPV. HrHPV prevalence peaked in the late 20 s and declined with increasing age. HrHPV positivity was inversely associated with having children living the household. In conclusion, HPV self-sampling is feasible and acceptable to Hopi women, and could be effective in increasing rates of cervical cancer screening in Hopi communities. HrHPV prevalence was similar to estimates in the general United States population.

Original languageEnglish (US)
Pages (from-to)1049-1061
Number of pages13
JournalJournal of Community Health
Volume41
Issue number5
DOIs
StatePublished - Oct 1 2016
Externally publishedYes

Fingerprint

Papillomavirus Infections
North American Indians
American Indian
community
Papanicolaou Test
cancer
Chi-Square Distribution
regression
Early Detection of Cancer
Uterine Cervical Neoplasms
Genotype
Polymerase Chain Reaction

Keywords

  • Acceptability
  • American Indian/Alaska Native (AI/AN)
  • Human papillomavirus (HPV)
  • Prevalence
  • Self-sampling

ASJC Scopus subject areas

  • Health(social science)
  • Public Health, Environmental and Occupational Health

Cite this

Winer, R. L., Gonzales, A., Noonan, C. J., Cherne, S. L., Buchwald, D. S., & for the Collaborative to Improve Native Cancer Outcomes (CINCO), T. C. T. I. N. C. O. CINCO. (2016). Assessing Acceptability of Self-Sampling Kits, Prevalence, and Risk Factors for Human Papillomavirus Infection in American Indian Women. Journal of Community Health, 41(5), 1049-1061. https://doi.org/10.1007/s10900-016-0189-3

Assessing Acceptability of Self-Sampling Kits, Prevalence, and Risk Factors for Human Papillomavirus Infection in American Indian Women. / Winer, Rachel L.; Gonzales, Angela; Noonan, Carolyn J.; Cherne, Stephen L.; Buchwald, Dedra S.; for the Collaborative to Improve Native Cancer Outcomes (CINCO), the Collaborative to Improve Native Cancer Outcomes (CINCO).

In: Journal of Community Health, Vol. 41, No. 5, 01.10.2016, p. 1049-1061.

Research output: Contribution to journalArticle

Winer, RL, Gonzales, A, Noonan, CJ, Cherne, SL, Buchwald, DS & for the Collaborative to Improve Native Cancer Outcomes (CINCO), TCTINCOCINCO 2016, 'Assessing Acceptability of Self-Sampling Kits, Prevalence, and Risk Factors for Human Papillomavirus Infection in American Indian Women', Journal of Community Health, vol. 41, no. 5, pp. 1049-1061. https://doi.org/10.1007/s10900-016-0189-3
Winer RL, Gonzales A, Noonan CJ, Cherne SL, Buchwald DS, for the Collaborative to Improve Native Cancer Outcomes (CINCO) TCTINCOCINCO. Assessing Acceptability of Self-Sampling Kits, Prevalence, and Risk Factors for Human Papillomavirus Infection in American Indian Women. Journal of Community Health. 2016 Oct 1;41(5):1049-1061. https://doi.org/10.1007/s10900-016-0189-3
Winer, Rachel L. ; Gonzales, Angela ; Noonan, Carolyn J. ; Cherne, Stephen L. ; Buchwald, Dedra S. ; for the Collaborative to Improve Native Cancer Outcomes (CINCO), the Collaborative to Improve Native Cancer Outcomes (CINCO). / Assessing Acceptability of Self-Sampling Kits, Prevalence, and Risk Factors for Human Papillomavirus Infection in American Indian Women. In: Journal of Community Health. 2016 ; Vol. 41, No. 5. pp. 1049-1061.
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