Abstract

This paper presents a new concept combining flexible organic light-emitting diode (OLED) display technology with fluorescent biorecognition microarray technology to fabricate point-of-care immunobiosensors. Our approach is designed to leverage commercial OLED display technology to reduce pre-functionalized biosensor substrate costs to pennies per cm2 combined with leveraging the display industries ability to manufacture an immense number of low-cost consumer electronic products annually. For this work, we demonstrate that our new approach using high brightness flexible OLED display technology combined with a charge integrating readout circuit and optical filters can offer point-of-care diagnostic sensitivity at or below 10 pg/mL, which approaches the lower limit of detection (LLOD) of typical clinical laboratory instrumentation.

Original languageEnglish (US)
Article number7270272
Pages (from-to)273-280
Number of pages8
JournalIEEE/OSA Journal of Display Technology
Volume12
Issue number3
DOIs
StatePublished - Mar 1 2016

Fingerprint

Organic light emitting diodes (OLED)
Health care
light emitting diodes
Display devices
Testing
optical filters
Clinical laboratories
bioinstrumentation
Consumer electronics
Optical filters
readout
brightness
Microarrays
industries
Biosensors
costs
filters
Costs
Luminance
sensitivity

Keywords

  • Biomarkers
  • flexible display
  • flexible electronics
  • fluorescent biorecognition
  • microarray
  • OLED
  • organic light emitting diodes (OLEDs)
  • point-of-care
  • thin-film transistors (TFTs)

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Smith, J. T., Katchman, B. A., Kullman, D. E., Obahiagbon, U., Lee, Y. K., O'Brien, B. P., ... Blain Christen, J. (2016). Application of Flexible OLED Display Technology to Point-of-Care Medical Diagnostic Testing. IEEE/OSA Journal of Display Technology, 12(3), 273-280. [7270272]. https://doi.org/10.1109/JDT.2015.2479457

Application of Flexible OLED Display Technology to Point-of-Care Medical Diagnostic Testing. / Smith, Joseph T.; Katchman, Benjamin A.; Kullman, Dixie E.; Obahiagbon, Uwadiae; Lee, Yong Kyun; O'Brien, Barry P.; Raupp, Gregory; Anderson, Karen; Blain Christen, Jennifer.

In: IEEE/OSA Journal of Display Technology, Vol. 12, No. 3, 7270272, 01.03.2016, p. 273-280.

Research output: Contribution to journalArticle

Smith JT, Katchman BA, Kullman DE, Obahiagbon U, Lee YK, O'Brien BP et al. Application of Flexible OLED Display Technology to Point-of-Care Medical Diagnostic Testing. IEEE/OSA Journal of Display Technology. 2016 Mar 1;12(3):273-280. 7270272. https://doi.org/10.1109/JDT.2015.2479457
Smith, Joseph T. ; Katchman, Benjamin A. ; Kullman, Dixie E. ; Obahiagbon, Uwadiae ; Lee, Yong Kyun ; O'Brien, Barry P. ; Raupp, Gregory ; Anderson, Karen ; Blain Christen, Jennifer. / Application of Flexible OLED Display Technology to Point-of-Care Medical Diagnostic Testing. In: IEEE/OSA Journal of Display Technology. 2016 ; Vol. 12, No. 3. pp. 273-280.
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