Appetite is correlated with octopamine and hemolymph sugar levels in forager honeybees

Christopher Mayack, Nicole Phalen, Kathleen Carmichael, Helen K. White, Frank Hirche, Ying Wang, Gabriele I. Stangl, Gro Amdam

Research output: Contribution to journalArticle

Abstract

Insects have rapidly changing energy demands, so they primarily rely on hemolymph and other carbohydrates to carry out life activities. However, how gustatory responsiveness and hemolymph sugar levels coordinate with one another to maintain energetic homeostasis in insects remains largely unknown for the highly social honeybee that goes through large physiological and behavioral changes. The potential role of biogenic amines and neuropeptides in the connection between the regulation of appetite and fluctuating sugar levels in the hemolymph, due to starvation, as the bee ages, was investigated. The largest appetite increase due to the starvation treatment was within the forager age class and this corresponded with an increase in octopamine levels in the brain along with a decline in hemolymph sugar levels. Adipokinetic hormone (AKH) was found in very small quantities in the brain and there were no significant changes in response to starvation treatment. Our findings suggest that the particularly dynamic levels of hemolymph sugar levels may serve as a monitor of the forager honeybee energetic state. Therefore, there may be a pathway in forager bees via octopamine responsible for their precise precipitous regulation of appetite, but to determine cause and effect relationships further investigation is needed.

Original languageEnglish (US)
JournalJournal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Fingerprint

Octopamine
octopamine
Hemolymph
honeybee
Appetite
appetite
hemolymph
honey bees
sugar
starvation
sugars
Starvation
Appetite Regulation
bee
Bees
brain
energetics
Insects
insect
Apoidea

Keywords

  • Aging
  • Biogenic amines
  • Hemolymph
  • Starvation
  • Trehalose

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Physiology
  • Animal Science and Zoology
  • Behavioral Neuroscience

Cite this

Appetite is correlated with octopamine and hemolymph sugar levels in forager honeybees. / Mayack, Christopher; Phalen, Nicole; Carmichael, Kathleen; White, Helen K.; Hirche, Frank; Wang, Ying; Stangl, Gabriele I.; Amdam, Gro.

In: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology, 01.01.2019.

Research output: Contribution to journalArticle

Mayack, Christopher ; Phalen, Nicole ; Carmichael, Kathleen ; White, Helen K. ; Hirche, Frank ; Wang, Ying ; Stangl, Gabriele I. ; Amdam, Gro. / Appetite is correlated with octopamine and hemolymph sugar levels in forager honeybees. In: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 2019.
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