Anxiety in patients with pheochromocytomas

M. N. Starkman, T. C. Zelnik, Randolph Nesse, O. G. Cameron

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Anxiety has been considered an important clinical feature of patients with pheochromocytomas. We studied 17 patients with active pheochromocytoma to determine whether they experienced anxiety that met criteria of the Diagnostic and Statistical Manual of Mental Disorders, third edition, for either panic disorder or generalized anxiety disorder. Fifty-two patients with primary anxiety disorders were used as a comparison group. Six patients with pheochromocytomas had norepinephrine-secreting tumors and 11 had mixed-secretion tumors, with elevated levels of both epinephrine and norepinephrine. None of the 17 patients described the severe apprehension of fear characteristic of panic attacks and none described agoraphobia. One patient received a diagnosis of possible panic disorder, two met criteria for generalized anxiety disorder, and two met criteria for major depressive episode. Thus, the elevated levels of catecholamines secreted by pheochromocytomas are not sufficient to elicit an anxiety disorder.

Original languageEnglish (US)
Pages (from-to)248-252
Number of pages5
JournalArchives of Internal Medicine
Volume145
Issue number2
DOIs
StatePublished - 1985
Externally publishedYes

Fingerprint

Pheochromocytoma
Anxiety
Anxiety Disorders
Panic Disorder
Norepinephrine
Agoraphobia
Diagnostic and Statistical Manual of Mental Disorders
Epinephrine
Fear
Catecholamines
Neoplasms

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Anxiety in patients with pheochromocytomas. / Starkman, M. N.; Zelnik, T. C.; Nesse, Randolph; Cameron, O. G.

In: Archives of Internal Medicine, Vol. 145, No. 2, 1985, p. 248-252.

Research output: Contribution to journalArticle

Starkman, M. N. ; Zelnik, T. C. ; Nesse, Randolph ; Cameron, O. G. / Anxiety in patients with pheochromocytomas. In: Archives of Internal Medicine. 1985 ; Vol. 145, No. 2. pp. 248-252.
@article{6551cff81a554ab7892ce6d0e86ca99a,
title = "Anxiety in patients with pheochromocytomas",
abstract = "Anxiety has been considered an important clinical feature of patients with pheochromocytomas. We studied 17 patients with active pheochromocytoma to determine whether they experienced anxiety that met criteria of the Diagnostic and Statistical Manual of Mental Disorders, third edition, for either panic disorder or generalized anxiety disorder. Fifty-two patients with primary anxiety disorders were used as a comparison group. Six patients with pheochromocytomas had norepinephrine-secreting tumors and 11 had mixed-secretion tumors, with elevated levels of both epinephrine and norepinephrine. None of the 17 patients described the severe apprehension of fear characteristic of panic attacks and none described agoraphobia. One patient received a diagnosis of possible panic disorder, two met criteria for generalized anxiety disorder, and two met criteria for major depressive episode. Thus, the elevated levels of catecholamines secreted by pheochromocytomas are not sufficient to elicit an anxiety disorder.",
author = "Starkman, {M. N.} and Zelnik, {T. C.} and Randolph Nesse and Cameron, {O. G.}",
year = "1985",
doi = "10.1001/archinte.145.2.248",
language = "English (US)",
volume = "145",
pages = "248--252",
journal = "JAMA Internal Medicine",
issn = "2168-6106",
publisher = "American Medical Association",
number = "2",

}

TY - JOUR

T1 - Anxiety in patients with pheochromocytomas

AU - Starkman, M. N.

AU - Zelnik, T. C.

AU - Nesse, Randolph

AU - Cameron, O. G.

PY - 1985

Y1 - 1985

N2 - Anxiety has been considered an important clinical feature of patients with pheochromocytomas. We studied 17 patients with active pheochromocytoma to determine whether they experienced anxiety that met criteria of the Diagnostic and Statistical Manual of Mental Disorders, third edition, for either panic disorder or generalized anxiety disorder. Fifty-two patients with primary anxiety disorders were used as a comparison group. Six patients with pheochromocytomas had norepinephrine-secreting tumors and 11 had mixed-secretion tumors, with elevated levels of both epinephrine and norepinephrine. None of the 17 patients described the severe apprehension of fear characteristic of panic attacks and none described agoraphobia. One patient received a diagnosis of possible panic disorder, two met criteria for generalized anxiety disorder, and two met criteria for major depressive episode. Thus, the elevated levels of catecholamines secreted by pheochromocytomas are not sufficient to elicit an anxiety disorder.

AB - Anxiety has been considered an important clinical feature of patients with pheochromocytomas. We studied 17 patients with active pheochromocytoma to determine whether they experienced anxiety that met criteria of the Diagnostic and Statistical Manual of Mental Disorders, third edition, for either panic disorder or generalized anxiety disorder. Fifty-two patients with primary anxiety disorders were used as a comparison group. Six patients with pheochromocytomas had norepinephrine-secreting tumors and 11 had mixed-secretion tumors, with elevated levels of both epinephrine and norepinephrine. None of the 17 patients described the severe apprehension of fear characteristic of panic attacks and none described agoraphobia. One patient received a diagnosis of possible panic disorder, two met criteria for generalized anxiety disorder, and two met criteria for major depressive episode. Thus, the elevated levels of catecholamines secreted by pheochromocytomas are not sufficient to elicit an anxiety disorder.

UR - http://www.scopus.com/inward/record.url?scp=0022003924&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022003924&partnerID=8YFLogxK

U2 - 10.1001/archinte.145.2.248

DO - 10.1001/archinte.145.2.248

M3 - Article

C2 - 3977483

AN - SCOPUS:0022003924

VL - 145

SP - 248

EP - 252

JO - JAMA Internal Medicine

JF - JAMA Internal Medicine

SN - 2168-6106

IS - 2

ER -