Abstract
An investigation of the Phillippine Ampelocissus sp. roots for cancer cell growth inhibitory components led to the isolation of a new acetogenin characterized as 22-epicalamistrin (1) employing primarily 2D NMR and high-resolution mass spectral analysis. Two other antineoplastic constituents proved to be the known acetogenin uvaribonin (2) and chalcone 3. Constituents 1-3 were all found to show significant cancer cell growth inhibitory activity against a panel of human cancer cell lines.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 130-133 |
| Number of pages | 4 |
| Journal | Journal of Natural Products |
| Volume | 71 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2008 |
ASJC Scopus subject areas
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry
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CCDC 698578: Experimental Crystal Structure Determination
Pettit, G. R. (Creator), Mukku, V. J. R. V. (Creator), Cragg, G. (Creator), Herald, D. L. (Creator), Knight, J. C. (Creator), Herald, C. L. (Creator), Chapuis, J. (Creator) & Pettit, G. R. (Creator), The Cambridge Structural Database, 2008
DOI: 10.5517/ccrfxsv, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccrfxsv&sid=DataCite
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