Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms

George Pettit; Fiona Hogan; Jun-Ping Xu; Rui Tan; Toshihiko Nogawa; Zbigniew Cichacz; Robin Pettit; Jiang Du; Qing Hua Ye; Gordon M. Cragg; Cherry L. Herald; Michael S. Hoard; Animesh Goswami; Justin Searcy; Larry Tackett; Dennis L. Doubek; Lee Williams; John N A Hooper; Jean M. Schmidt; Jean Chapuis; Denise N. Tackett; Felicia Craciunescu

doi:10.1021/np700738k

Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms

George Pettit, Fiona Hogan, Jun-Ping Xu, Rui Tan, Toshihiko Nogawa, Zbigniew Cichacz, Robin Pettit, Jiang Du, Qing Hua Ye, Gordon M. Cragg, Cherry L. Herald, Michael S. Hoard, Animesh Goswami, Justin Searcy, Larry Tackett, Dennis L. Doubek, Lee Williams, John N A Hooper, Jean M. Schmidt, Jean ChapuisDenise N. Tackett, Felicia Craciunescu

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C (1), axinastatin 5 (5), bengazoles A (6), B (7), and E (8), manzamine A (10), jaspamide (11), and neoechinulin A (19) has been summarized.

Original language	English (US)
Pages (from-to)	438-444
Number of pages	7
Journal	Journal of Natural Products
Volume	71
Issue number	3
DOIs	https://doi.org/10.1021/np700738k
State	Published - Mar 2008

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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Pettit, G., Hogan, F., Xu, J.-P., Tan, R., Nogawa, T., Cichacz, Z., Pettit, R., Du, J., Ye, Q. H., Cragg, G. M., Herald, C. L., Hoard, M. S., Goswami, A., Searcy, J., Tackett, L., Doubek, D. L., Williams, L., Hooper, J. N. A., Schmidt, J. M., ... Craciunescu, F. (2008). Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms. Journal of Natural Products, 71(3), 438-444. https://doi.org/10.1021/np700738k

Pettit, G, Hogan, F, Xu, J-P, Tan, R, Nogawa, T, Cichacz, Z, Pettit, R, Du, J, Ye, QH, Cragg, GM, Herald, CL, Hoard, MS, Goswami, A, Searcy, J, Tackett, L, Doubek, DL, Williams, L, Hooper, JNA, Schmidt, JM, Chapuis, J, Tackett, DN & Craciunescu, F 2008, 'Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms', Journal of Natural Products, vol. 71, no. 3, pp. 438-444. https://doi.org/10.1021/np700738k

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abstract = "Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C (1), axinastatin 5 (5), bengazoles A (6), B (7), and E (8), manzamine A (10), jaspamide (11), and neoechinulin A (19) has been summarized.",

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AU - Pettit, George

AU - Hogan, Fiona

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AU - Tan, Rui

AU - Nogawa, Toshihiko

AU - Cichacz, Zbigniew

AU - Pettit, Robin

AU - Du, Jiang

AU - Ye, Qing Hua

AU - Cragg, Gordon M.

AU - Herald, Cherry L.

AU - Hoard, Michael S.

AU - Goswami, Animesh

AU - Searcy, Justin

AU - Tackett, Larry

AU - Doubek, Dennis L.

AU - Williams, Lee

AU - Hooper, John N A

AU - Schmidt, Jean M.

AU - Chapuis, Jean

AU - Tackett, Denise N.

AU - Craciunescu, Felicia

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Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms

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