Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms

George Pettit, Fiona Hogan, Jun-Ping Xu, Rui Tan, Toshihiko Nogawa, Zbigniew Cichacz, Robin Pettit, Jiang Du, Qing Hua Ye, Gordon M. Cragg, Cherry L. Herald, Michael S. Hoard, Animesh Goswami, Justin Searcy, Larry Tackett, Dennis L. Doubek, Lee Williams, John N A Hooper, Jean M. Schmidt, Jean ChapuisDenise N. Tackett, Felicia Craciunescu

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C (1), axinastatin 5 (5), bengazoles A (6), B (7), and E (8), manzamine A (10), jaspamide (11), and neoechinulin A (19) has been summarized.

Original languageEnglish (US)
Pages (from-to)438-444
Number of pages7
JournalJournal of Natural Products
Volume71
Issue number3
DOIs
StatePublished - Mar 1 2008

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms'. Together they form a unique fingerprint.

  • Cite this

    Pettit, G., Hogan, F., Xu, J-P., Tan, R., Nogawa, T., Cichacz, Z., Pettit, R., Du, J., Ye, Q. H., Cragg, G. M., Herald, C. L., Hoard, M. S., Goswami, A., Searcy, J., Tackett, L., Doubek, D. L., Williams, L., Hooper, J. N. A., Schmidt, J. M., ... Craciunescu, F. (2008). Antineoplastic Agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms. Journal of Natural Products, 71(3), 438-444. https://doi.org/10.1021/np700738k