Antineoplastic agents. 52. Baileya multiradiata.

G. R. Pettit, C. L. Herald, G. F. Judd, G. Bolliger, L. D. Vanell, E. Lehto, C. P. Pase

Research output: Contribution to journalArticle

Abstract

The desert-marigold Baileya multiradiata Harv. and Gray (Compositae) has been found to produce a series of sesquiterpenes that markedly inhibit growth of the murine lymphocytic leukemia P388 and the corresponding in vitro cell line. Separation guided by bioassay led to the isolation of baileyin (1), fastigilins B and C (3a and 2a), radiatin (3b), pleniradin (4a), and the new pseudoguaianolide multiradiatin (2b). The most significant antitumor activity was displayed by fastigilin C (2a) and radiation (3b).

Original languageEnglish (US)
Pages (from-to)29-36
Number of pages8
JournalLloydia
Volume41
Issue number1
StatePublished - Jan 1978
Externally publishedYes

Fingerprint

Leukemia P388
Lymphoid Leukemia
Asteraceae
Sesquiterpenes
Bioassay
Biological Assay
Antineoplastic Agents
Cells
Radiation
Cell Line
Growth
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pettit, G. R., Herald, C. L., Judd, G. F., Bolliger, G., Vanell, L. D., Lehto, E., & Pase, C. P. (1978). Antineoplastic agents. 52. Baileya multiradiata. Lloydia, 41(1), 29-36.

Antineoplastic agents. 52. Baileya multiradiata. / Pettit, G. R.; Herald, C. L.; Judd, G. F.; Bolliger, G.; Vanell, L. D.; Lehto, E.; Pase, C. P.

In: Lloydia, Vol. 41, No. 1, 01.1978, p. 29-36.

Research output: Contribution to journalArticle

Pettit, GR, Herald, CL, Judd, GF, Bolliger, G, Vanell, LD, Lehto, E & Pase, CP 1978, 'Antineoplastic agents. 52. Baileya multiradiata.', Lloydia, vol. 41, no. 1, pp. 29-36.
Pettit GR, Herald CL, Judd GF, Bolliger G, Vanell LD, Lehto E et al. Antineoplastic agents. 52. Baileya multiradiata. Lloydia. 1978 Jan;41(1):29-36.
Pettit, G. R. ; Herald, C. L. ; Judd, G. F. ; Bolliger, G. ; Vanell, L. D. ; Lehto, E. ; Pase, C. P. / Antineoplastic agents. 52. Baileya multiradiata. In: Lloydia. 1978 ; Vol. 41, No. 1. pp. 29-36.
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